Objective: To monitor cervical squamous cell carcinoma stage III patients before and after radical radiotherapy serum squamous cell carc inoma antigen(SCC-Ag) level and changes in cervical cytology(TCT) examination, and explore joint TCT SCC-Ag in cervical squamous stage III cancer radical radiotherapy efficacy and clinical value of prognosis.Methods: A retrospective analysis from April 2013 to April 2014 in the diagnosis and treatment of 72 patients Medical Gynecologic Oncology Tumor Hospital of Guangxi, all cases by histopathological diagnosis of cervical squamous cell carcinoma stage III, and for the first time in our hospital radical radiotherapy. Before and after treatment on a regular basis using micropartic le enzyme immunoassay serum SCC-Ag value detecting patients, and liquid-based cytology TCT examination. Evaluation of cervical squamous cell carcinoma Phase III efficacy of radical radiotherapy and understand the patient’s prognosis based on the detection result of SCC-Ag and TCT.Results: 72 cases of cervical squamous cell carcinoma stage III patients with serum SCC-Ag positive rate was 75.0%, positive expression and clinical stage SCC-Ag, the histological extent unrelated(P> 0.05), tumor size and tumor, perivascular lymph node metastasis(P <0.05). Serum SCC-Ag concentration was significant difference(P <0.05) before and after radical radiation therapy. The positive rate of TCT examination and clinical stage, histological grade, tumor size, lymph node metastasis perivascular(P> 0.05), a s ignificant difference(P <0.05) TCT positive rate between before and after treatment. The diagnostic value of using serology joint TCT SCC-Ag is superior to both single examination, can accurately evaluate the efficacy and prognosis.Conclusion: The serum SCC-Ag expression and tumor size, lymph node metastasis was significantly related to the larger tumor or presence of tumor lymph node metastas is, the higher the serum SCC-Ag expression levels. SCC-Ag joint TCT examination to evaluate the efficacy of radical radiotherapy in cervical squamous cell carcinoma of the III correctly determine prognosis. |