Purpose: TO study the serum squamous cell carcinoma antigen levels in clinical decision making for patients with cervical cancer of aftertreatment adjuvant radiotherapy. Methods: preoperative peripheral blood serum SCC-ag levels in 132 early-stage cervical cancer patients (Ib -early stage IIb)was examined by enzyme immunoassay method. Result: The diffences between the aftertreatment adjuvant radiotherapy groups and the groups without aftertreatment adjuvant radiotherapy showed evident significence(P<0.01).In patients with normal preoperative SCC-ag, 17% of IB had postoperative indications for adjuvant radiotherapy. In patients with elevated ( > 2ng/ml) serum SCC-ag, 58% of IB had postoperative indications for adjuvant radiotherapy; in contrast to 23% and 74% of IIa/early IIb patients with normal and elevated ( > 2ng/ml) serum SCC-ag (p < 0.001). Conclusion: serum SCC-ag levels could supervise pre-and protherapy of cervical cancer and be one of tools of forecast multiple therapies of cervical cancer.
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