The Effects Of Pre-pregnancy And Different Periods Of Pregnancy Body Mass Index On Gestational Diabetes Mellitus And Macrosomia

Background and objective: At present,there are a lot of researches about relations between pre-pregnancy and different periods of pregnancy body mass index, gestational diabetes mellitus and macrosomia.However, they are mostly from the viewpoint of pre-pregnancy and overall increase about BMI, and there are still no uniform conclusions.However, pregnancy is a continuous process, and exploring the relationship between pre-pregnancy and different periods of pregnancy BMI is also very necessary. Retrospective analysis was made of 2260 pregnancy women data. The purpose of this paper is to study the relationship between pre-pregnancy and three different periods of pregnancy BMI with GDM and macrosomia, and the relationship between pre-pregnancy and three different periods of pregnancy BMI with macrosomia for those women who were diagnosed with GDM.Methods: First, to calculate and compare the incidence of GDM and macrosomia of various groups according to different BMI for each period in pregnancy. And the second, to calculate the incidence of macrosomia in all different non-GDM pregnant groups.Thirdly, to calculate the incidence of macrosomia in GDM and non-GDM groups, then calculate the incidence of macrosomia in all various GDM groups with different pre-pregnancy and three different periods of pregnancy BMI.Results:(1) The incidence rates of macrosomia and GDM increased significantly inthose women whose pre-pregnancy and early pregnancy BMI were greater than or equal to 24 Kg/m2. The incidence rates of GDM increased significantly in those women whose second trimester BMI were greater than or equal to 28 Kg/m2, and the incidence rate of macrosomia was proportional to the second trimester BMI. The third trimester BMI have no influence on the incidence of GDM, but was proportional to the incidence of macrosomia.(2) In non-GDM pregnant women, the incidence rates of macrosomia in pre-pregnancy obesity and overweight groups were higher than other groups, and the incidence rate of macrosomia was proportional to early pregnancy, the second trimester and the third trimester BMI.(3) The incidence of macrosomia in GDM group was higher than non-GDM group.For GDM women whose pre-pregnancy and each period of pregnancy BMI were greater than or equal to 28 Kg/m2, the incidence rate of macrosomia increased significantly.Conclusions: The study showed that the incidence of GDM increased significantly in those women whose pre-pregnancy and early pregnancy BMI were greater than or equal to 24 Kg/m2 and whose second trimester BMI was greater than or equal to 28 Kg/m2. The incidence rate of macrosomia increased significantly in those women whose pre-pregnancy and early pregnancy BMI were greater than or equal to 24 Kg/m2, and it was proportional to the second and the third trimesters BMI. In non-GDM pregnant women, the incidence rates of macrosomia in pre-pregnancy obesity and overweight groups were higher than others, and the incidence rate of macrosomia was proportional to early pregnancy, the second trimester and the third trimester BMI. For GDM women whose pre-pregnancy and each period of pregnancy BMI were greater than or equal to 28 Kg/m2, the incidence rate of macrosomia increased significantly.