| Objective:The study collected from jiangsu province hospital endocrinology and gynecology outpatient cases of PCOS patients, and analysis of TCM syndrome type distribution, provide the basis for the syndrome differentiation and treatment of PCOS。This study by detecting glycolipids function in patients with PCOS, the levels of sex hormones, observe its relevance, to analyze its influencing factors, provide the basis for clinical diagnosis and treatment.Methods:The study obtained from Jiangsu province hospital endocrinology and gynecology outpatient cases of patients with PCOS, under the2011polycystic ovary syndrome diagnostic criteria (health) of industry choice in patients with PCOS,collect patients’ age, duration of PCOS, TCM symptoms, tongue, pulse, etc.It induces the TCM syndrome type, and analysis of the distribution regularity of TCM syndrome types。It collect patients’ general information, record the menstruation situation, clinical performance, high androgen hormones, blood glucose, insulin and blood lipids index, to analyze its influencing factors, to explore the clinical significance and correlation between them.Results:①This study collected213cases of PCOS patients, aged16～42(28.36+4.01), closed with phlegm dampness type73cases (324.3%), and qi stagnation and blood stasis type60cases (28.2%), kidney deficiency type of37cases (27.4%), liver meridian syndrome43cases (20.2%).②Adolescence group compared with TCM syndrome type of childbearing age group:adolescent group of closed liver syndrome, phlegm dampness type than of childbearing age group (P<0.05and P<0.01);Qi stagnancy and blood stasis type of childbearing age group than adolescent group (P<0.05).③213PCOS patients on the basis of BMI is divided into the early stage of the normal size, obese body, obesity group and normal size67cases (31.5%),98cases of obesity early size (46.0%), obese figure48cases (22.5%).④Compared with the normal size, the early stage of the obesity group T, LH increased (P<0.05), and obesity group size T, LH increased significantly (P<0.01), FSH, E2, P, PRL were no obvious difference (P>0.05).⑤Closed compared with kidney deficiency type, phlegm dampness, T elevated liver meridian syndrome patients (P<0.05), closed phlegm dampness, qi and blood stasis patients with LH increased (P<0.05);Compared with qi and blood stasis syndrome, phlegm wet resistance type, closed liver meridian syndrome patients with FSH reduced (P<0.05).⑥Compared with the normal size, obesity early size group, rising obesity group size FINS, TC, TG (P<0.05～0.01);Compared with the normal size, obesity early high HDL-C reduce size with obesity group (P<0.05).⑦Compared with qi and blood stasis, kidney empty, closed phlegm dampness type, liver meridian syndrome FBG, FINS, TC, TG increased (P<0.05), HDL-C lower (P<0.05), LDL-C did not see obvious difference (P>0.05).⑧T and FBG, FINS, TC, TG, HDL and LDL-C-C were positively correlated (P<0.05～0.01).⑨T, FBG, FINS and TC, TG, HDL-C and LDL-C were positively correlated (P<0.05～0.01).⑩Multiple stepwise regression analysis showed that FSH, LH, E2, FBG, FINS for T independent factors.Conclusion:①213patients with PCOS in TCM syndrome type distribution is phlegmy wet resistance closed type> blood stasis type>liver meridian syndrome> kidney qi stagnancy.②Adolescence groups see more closed phlegm dampness, and adolescent obesity, eating habits;Of childbearing age group see qi and blood stasis, and the modern factors.③In this study group,normal size67cases (31.5%), the early stage of the obese body group98cases (46.0%), fat body group48cases (22.5%),Obesity may be associated with HI/IR PCOS, obese PCOS patients were more prone to IR, the fueling PCOS is given priority to with LH rise, fueling PCOS is given priority to with abnormal insulin secretion.④Polycystic ovary syndrome in patients dyslipidemia in patients with mainly characterized by TG, LDLC levels, HDL-C levels.Polycystic ovary syndrome in patients with obesity, HI, sugar, lipid metabolic disorder and IR etc. The performance of the metabolic syndrome. |
PDF Full Text Request