| ObjectiveBronchiectasis is a kind of psychosomatic diseases which is recurrent, difficult to cure and the bronchial tree become permanent expansion. It can not only cause chronic respiratory symptoms, such as cough, hemoptysis and expectoration, but also loss lung.function and worse quality of life. It is knew that the bronchiectasis is prevalent to feel unhealthy emotion, such as anxiety and depression, which plays an important role in the deve-lopment of the disease.The study was to investigate the relationship between anxiety and de-pression symptoms and quality of life in stable bronchiectasis. There were two aims. One was to understand the condition about anxiety and depression emotion in a sample of patients with bronchiectasis in stable, explore its influence factors, and evaluate the relationship between quality of life and it, in order to provide the reference for the psychological intervene-tion in bronchiectasis. The other was to analyse the factors about quality of life of patients with bronchiectasis systematically, and that be good to provide the basis for improving the patients’quality of life.MethodsThis cross-sectional study included95adult patients with bronchiec-tasis in Guangdong Province Traditional Chinese Medical Hospital. Patients completed the hospital anxiety and Depression Scale, the St George’s Re-spiratory Questionnaire and basic information questionnaire.Results1. Bronchiectasis in a period of stability, had anxiety and depression which were accounted for61.1%in this study.49.47%had been elevated de-pression-related scores,43.16%had been elevated anxiety-related scores, and31.6%had been elevated both two scores. Depression scores which patients had hemoptysis,fungal and Pseudomo-nas aeruginosa infection were higher than those of the other patients(P<0.05,0.05,0.01). Depression scores of bronchiectasis were positively corre-lated with age, occupation, the daily amount of expectoration, hemoptysis volume level, the number of exacerbations, bronchial injury scores (P<0.01), sputum color, course of disease, and complications(P<0.05), while negatively correlated with education, and the frequency of psychotropic drug use(P<0.01).Anxiety scores of patients who had been infected with Pseudomonas aeruginosa were higher than that of the other patients’(P<0.01). Anxiety scores of bronchiectasis were positively correlated with daily amount of expectoration, hemoptysis volume level, and that negatively correlated with per capita income monthly (P<0.05).2. Scores of quality of life, respiratory symptoms, activity limitation of and disease effects, which bronchiectasis had Pseudomonas aeruginosa infection, were higher than those of the other patients (P<0.01,0.01,0.05,0.01).Scores of respiratory symptoms were positively correlated with occu-pation (P<0.05), age, the course of disease, complication, the daily amount of expectoration, sputum color, sputum quality, the number of exacerbations and scores of bronchial injury (P<0.01), and negatively correlated with educa-tional (P<0.01).Activity limitation scores were positively correlated with marital status, comorbidities (P<0.05), age, occupation, course of disease, complica-tion, the daily amount of expectoration, the quality of sputum, the number of exacerbations and scores of bronchial injury(P<0.01), while negatively correlated with the education, bronchiectasis etiology, and the frequency of psychotropic drug use(P<0.01).Disease effects scores positively were correlated with age, occupation, the course of disease, complication, the daily amount of expectoration, the number of exacerbations, scores of bronchial injury (P<0.01), sputum color, quality of sputum, and level of hemoptysis volume(P<0.05), while negatively correlated with education and the frequency of psychotropic drug use(P<0.01). Quality of life scores were also positively correlated with marital status, bronchiectasis etiology(P<0.05), age, occupation, course of disease, complication, the daily amount of expectoration, sputum color, the number of exacerbations and bronchial injury scores(P<0.01), negatively correlated with education and the frequency of psychotropic drug use(P<0.01).3. Scores of anxiety were positively correlated with scores of quality of life and scores of disease effects(P<0.01), and hardly correlated with respiratory symptoms and limitation of activity significantly.Depression scores were positively correlated with scores of quality of life, symptoms of respiretory, limitation of activity and disease effects evidently (P<0.01),and the correlation coefficients were0.696,0.476,0.570,0.720respec-tively.Scores of quality of life among groups(neither emotion group, anxiety group, depression group, combination of emotion group), the difference was statistically significant (P<0.01). Among them, that neither emotion group was compared with the depression group and combination of emotion group respectively, and results statistically were significantly different.(P<0.01)That anxiety group compared with the depression group and combination of emotion group respectively, was statistically significant differences.(P<0.01)4. The most important factors were depression emotion and the number of exacerbations which could enter the regression equation in the total factors associated with scores of quality of life in bronchiectasis.Conclusion1. It was prevalent with anxiety and depression in patients, and often the two emotions exist at the same time in stable bronchiectasis. There were many influent factors.It was easier to give rise to depression in bronchiectasis patients, who had hemoptysis, pseudomonas aeruginosa and fungal infection than that of the other patients. Depression of patients would had been more serious along with the longer course of disease, the growth of age, daily amount of expectoration, hemoptysis volume level, the number of exacerbations, bron-chial injury score, the frequency of psychotropic drug use, and the compli-cations. In addition, bronchiectasis who had lower education, the loss of occupation and abnormal sputum color, would also produce the depression more obviously than the other.Similarly, it was more likely to cause more serious anxiety emotion in bronchiectasis,who had the more daily amount of expectoration,more hemop-tysis volume level, pseudomonas aeruginosa infection, and less per capita income monthly.2. Quality of life with stable bronchiectasis was closely related to individual, society and disease factors. That scores of quality of life, re-spiratory symptoms, activity limitation and disease effects, would had been higher more and more, along with the growth of age, the daily amount of ex-pectoration, the number of exacerbation, and bronchial injury score,besides the increasing complication, the longer course of disease, the lower educa-tion, the loss of occupation and pseudomonas aeruginosa infection. In short, quality of life would been decreasing. The respiratory symptoms were also correlated with sputum color and sputum quality. Activity limitation were still correlated with marital status, the comorbidities, quality of sputum, the bronchiectasis etiology, and the frequency of psychotropic drug use. Disease effects were also close correlated with sputum color, quality of sputum, the level of hemoptysis and the frequency of psychotropic druguse. Quality of life was correlated with marital status, bronchiectasis etiolo-gy, sputum color and the frequency of psychotropic drug use too.3. The relationship among anxiety, depression and quality of life in bronchiectasis patients of stability was extremely close.They interacted each other.There was a significant positive correlation with the overall quality of life, disease effects and anxiety emotion. Moreover, depression had the high significant positive correlation with the overall quality of life, respiratory symptoms, activity limitation, and disease effects.There were significantly different about quality of life in patients of bronchiectasis who had anxiety, or depression, or both or neither. Quali-ty of life in patients with simply depression and combination of emotion was more significant and more serious, than those with neither emotion and pure anxiety patients.4. That can forecast quality of life in stable bronchiectasis patients were depression and the number of exacerbations among many factors. |
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