Clinical Study On The Effect Of Cang Fu Dao Tan Decoction Combined With Lifestyle Adjustment Treating Obese Women With Polycystic Ovary Syndrome

ObjectiveThis research trough clinical observation to study the effect of Cang Fu Dao Tan decoction combined with lifestyle adjustment in the treatment of obese women with Polycustic Ovary Syndrome.MethodsThis research selected66patients fitting the criteria of Polycystic Ovary Syndrome. The patients were randomly and evently divided into two groups, the treatment group and the controll group. The treatment group were treated with Cang Fu Dao Tan decoction combined with lifestyle adjustment and the controll group were treated with only Cang Fu Dao Tan decoction. All of the patients were observed for3months. The observation focused on two points, the clinical symptoms which included with the menstrual cycle, the traditional Chinese medicine syndrome, the basal body temperature (BBT) and the pregnancy, Clinical indicators was the other point which consist of Body mass index (BMI), Ovarian volume, Follicle-stimulating hormone(FSH),Luteinizing hormone (LH), LH/FSH, Testosterone (T), Fasting insulin (FINS), Fasting plasma glucose (FPG), HOMA-IR and Insulin-like growth factor-I (IGF-I). This research amided at comparing the both points before and after treatment of two groups.ResultsThe treatment group was superior to the controll group in clinical curative effect. The traditional chinese medicine symptoms integral decreased obvously in both groups afer treatment. The effective rate of TCM symptoms in the treatment group was91.67%while the control group was81.82%, the difference is statistically significant. The menstrul cycle was shortened afer treatment of both groups, the effect of the treatment group was better than the control group and the difference is statistically significant. The levers of FINS、 HOMA-IR、IGF-I were all obvously lower than those of pretherapy, Ovarian volume and BMI were no exception, similarly, the effect of the treatment group was superior to the control group and the difference is statistically significant. The level of LH、T and LH/FSH were lower afer treatment while there were no significant about LH and LH/FSH between two groups except T which the treatment group was superior. The ratio of patients’ BBT which presented typical double phase in the treatment group was higher than the control group during therapy while the rate of pregnancy was no significant. There was no difference of the lever of FSH、FPG between before and afer treatment for two groups.ClonclusionThe effect of Cang Fu Dao Tan decoction combined with lifestyle adjustment in the treatment of obese women with Polycustic Ovary Syndrome is distinct. The total curative effective rate in the treatment group was up to87.5%. The combination therapy methed can improved TCM symptom of phlegm dampness stagnation effectively, lowerd BMI and reduced the ovarian volume, Reduce the ovarian volume. Reproductive endocrine disorder can be balanced and the insulin resistance can be corrected through the combination therapy method which used for reducing the lewer of IGF-I. The combination therapy methed was effective in restoring ovulation and shortening the menstrual cycle. All in all, the combination therapy methed is one of the effective treatment options in the treatment of obese women with Polycustic Ovary Syndrome.