Study On The Clinical Efficacy Of Biantongxiaoqinglong Decoction In Treating Chronic Cor Pulmonale

ObjectiveThis study is to make an objective assessment for the efficiency of biantongxiaoqinglong decoction in treating chronic cor pulmonale, also to look for its advantage, and to evaluate its safety.All is to provide evidencefor the more doctor to use the biantongxiaoqinglong decoction.MethodsThe60cases of chronic cor pulmonale patients who met the inclusion criteria were equally divided into two groups---one is the therapy group (taking biantongxiaoqinglong decoction) and the other one is the control group(taking the combined therapy of Chinese and Western medicine) by the synchronized nonrandom methods. The symptom scores and the effect were used as the evaluation index and the scores were made at24,72, hours and2weeks, after treatment.90days later, we followed up the patients, that if they haved went to the hospital for chronic cor pulmonale. The number of who had went to the hospital had been writen down. The therapy group which decoction they have tade and how much were wrote down strictly. Then, the statistical data was set up and the efficacy was analyzed with SPSS18.0. The short-term efficacy of biantongxiaoqinglong decoction was explored and compared its advantages with control group.ResultsSymptom scores:Compared with each group, there was no significant difference in effective rate. Each group can control the symptom of chronic cor pulmonale. However, the therapy group is superior to control group in improving the general symptoms, just as fatigue, diarrhea, abdominal distension, limbs cold and anorexia. The control group is superior to therapy group in improving the symptoms of patients about the lung, just as shortness of breath, cough and chest tightness.The effect values:There was no significant difference in effective rate at24hours72hours. So we can see there was no different in the shorten effect for the two groups.90-day recurrence rate:The therapy group is twenty percent and the control group is fifty percent. The90-day recurrence rate of the therapeutic group was lower than that of the control group. There was no significant difference in90-day recurrence rate.Safety Evaluation:Some patients in the therapeutic group after taking medicine, can appear red face, the network or floating pontoons, shortness of breath, sweating, and other harmful response. When we adjust the medicine that to stabilize their primordial yang, the shortness of breath is improved.It tells us when we use the biantongxiaoqinglong decoction we should assess the constitution of the patients.ConclusionThe short-term efficacy of two groups is equivalent, however the therapy group is superior to the control group in improving the general symptoms and reducing the90-day recurrence rate.