The Study Of The Relativity Between The0-14Years Old Children Helicobacter Pylori Infection And Recurrent Respiratory Tract In Dali Region

[objective]Repeated respiratory infection is a common condition in children, children withserious damage to health of body and mind, but the exact cause of infantile repeatedrespiratory infection isn’t entirely clear, now considered to be a result of the combinedaction of multiple factors. helicobacter pylori (HP) infection is anothe commoncondition in children. And recurrent respiratory tract infections associated with HPinfection has not yet been reported at home and abroad. In this paper, at the same timein Dali region age0to14different ages of recurrent respiratory tract infections inchildren line HP stool antigen detection and determination of the humoral immunefunction, further study on the correlation between HP infection and recurrentrespiratory tract infections, for infantile repeated respiratory infection, treatment andprevention of HP infection disease provide a certain amount of science[methods]1.one week before specimen collection did not use any antimicrobials,30minutes after specimen collection test or cryogenic refrigerator for seal is based on the Chinesemedical association branch of pediatrics breathing group of recurrent respiratory tractinfections clinical standard:(1)0to2years old children, more than7times in a yearthe upper respiratory tract infection, lower respiratory tract infectionstracheobronchitis more than three times, more than2times pneumonia;(2)3to5years old children, upper respiratory tract infection more than six times a year, lowerrespiratory tract infections tracheobronchitis more than2times, more than2times pneumonia;(3)6~14years old children, upper respiratory tract infection for morethan five times a year, lower respiratory tract infections tracheobronchitis more than2times, pneumonia more than2times. The above standard upper respiratory tractinfection from1second time interval at least more than7days. If the number of upperrespiratory tract infection is not enough, can be combined with lower respiratory tractinfections frequently, the opposite is not established;1years to be seen; Recurrentpneumonia refers to pneumonia2or more times in a year[28]. But need to rule outmalnutrition, lack of iron deficiency anemia, vitamin, trace element deficiency,congenital heart disease, stomach esophagus reflux, bronchial asthma, chronicpneumonia, diseases such as allergic rhinitis, tonsillitis, and history. Repeatedrespiratory infection group and control group according to age is divided into threestages:0to2years,3to5years,6to14years old.60cases of children with recurrentrespiratory tract infections are divided into: HP positive group25cases; HP negativegroup of35cases. A random sample to the hospital to see a doctor in the same periodof60cases of children with recurrent respiratory tract infections as control group.Eliminate diseaese of the control group are same to the research group,and HP stoolantigen test is not used within a week before.Children with recurrent respiratory tractinfection group and control group after admission before using antimicrobials withsterile container collection lines shit shit HP antigen determination and phlebotomizeIgG, the IgA, determination of content of IgM.2.The measurements1) with helicobacter pylori antigen detection reagent method (emulsion) HP stoolantigen detection.2) immune turbidity method of determination of serum immunoglobulin IgG, theIgA,IgM.3. The statistical methodsThe experimental data are used spss16.0software for statistical analysis andprocessing, data are expressed as a mean standard deviation.The significance test ofdifference between the two groups by using two independent sample card square test,the control group, the HP positive group and negative group, comparing single factor analysis of variance between all inspection level for a=0.05, P <0.05, with statisticalsignificance.[results]1.60cases RRTI group and60cases of control group comparison: RRTI group thancontrol group in the HP positive rate is high, the difference was statistically significant(P <0.01).2.three ages RRTI group compared with control group①0to2years old: RRTI group than the control group HP positive rate is high, thedifference was statistically significant (P <0.01).②3to5years old: RRTI group than the control group HP positive rate is high, thedifference was statistically significant (P <0.05).③6to14years old: RRTI group compared with control group, there was nostatistically significant difference (P>0.05).3.three stages of age control group HP, HP positive group and negative groupcomparison between serum immunoglobulin①0-2years old: the control group and HP positive group and the control group andnegative group of IgM are differences significant (P <0.05), there were no significantdifferences in IgG, IgA, P>0.05;HP positive group and negative group, in contrast,IgG, IgA and IgM had no significant difference, P>0.05, no statistical significance.②3-5years old: the control group and HP positive IgM between HP group, controlgroup and negative group were no significant difference (P>0.05);Control group andHP positive group comparison, there were no significant differences in IgG, IgA, P>0.05;HP control group and negative group comparison, IgG, IgA are significantdifference, P <0.05;HP HP positive group and negative group, in contrast, IgG, IgA,there was no significant difference, P>0.05, no statistical significance.③6to15years old: the control group and HP HP positive group and the controlgroup and negative group, the HP HP positive group and negative group and IgG, IgAand IgM had no significant difference, P>0.05, no statistical significance.[conclusion]1. Repeated respiratory tract infection (RRTI) set of HP positive rate is higher than th e control group, Dali region infantile repeated respiratory infection and there is a certain correlation between helicobacter pylori infection, the speculation Helicobacter pylori infection is likely to be an important pathogenic factor of infantile repeated respiratory infection.2. Different age children immune globulin is different, however,overall childhood helicobacter pylori infection and humoral immune change has no obvious correlation,foreach age group sample size is not big enough and measuring IgA serotype, cannot fully reflect the IgA immune status, remains to be further in-depth study.