Clinical Research Of Amidi On Treating Cough Variant Asthma

ObjectiveCough variant asthma is a special type of bronchial asthma, Children, regardless ofage, Cough is the main or even the only clinical manifestation. Persistent or recurrentcough more than1month. The night or early morning attack. Irritating cough, Virusinfection, exposure to cold air or dust after exercise, easy to induce cough. Withoutobvious clinical asthma, dyspnea, shortness of breath and other symptoms or signs.Nosigns of infection, Through long-term antibiotic treatment is invalid.At the same time,patients may have a personal or family history of allergy and high reaction of airway.Inrecent years, cough variant asthma incidence rate increased gradually.And graduallybecome the most common cause of chronic cough. Because the disease can occur at anyage，the only symptoms can be just as cough and no obvious positive signs, Very easy tobe erroneous diagnosis of bronchitis, recurrent respiratory tract infection. So to study, life,mental patients bring great distress. Pathogenesis of cough variant asthma is generallybelieved that the same and bronchial asthma. It is persistent airway inflammation andairway hyperresponsiveness characteristics. The principle of treatment of bronchial asthmacan achieve better efficacy. Beta2receptor agonists are effective bronchodilators. Shorteffect such as albuterol, terbutaline is the most effective bronchodilators At presentadvocate inhalation on-demand in symptomatic. If symptoms do not fully control, hormoneinhalation can be used as a supplementary therapy. Short-acting agonist dose was <3-4times a day, each time2lift,1lift for100ug. In conventional dose not control, generallyno longer increase the dosage, long-acting agonists such as Sami Tero, oral or inhaledformoterol can be used. Sometimes some children age is small, cannot match the inhalation,and even refused to suction. which affects the treatment result. Some children taking thedrug difficult, forced feeding can appear cough, vomiting, intense crying and otherphenomena, which bring trouble to the treatment of cough variant asthma. Amidi also istulobuterol.As can be attached to the chest, back and upper arm can be reduce the pain of patients, Amidi famous tulobuterol, is a kind of long-term, highly selective Beta2receptoragonists.With the expansion of bronchial role, at the same time have allergy, promotebronchial ciliated motion. To alleviate the symptoms, and relieve the children oral orinhaled drugs.MethodsIn this study,3-11years old of100patients of cough variant asthma were randomlydivided into two groups,50patients in each group. The control group was givenantihistamine drugs combined with leukotriene receptor antagonist treatment.. Theexperimental group was treated with inhaled corticosteroids, with Amie Di, every night1stickers, affixed to the chest, back and upper arm.. Treatment and observation can be usedexpectorant, cough medicine, anti-infective drugs during. Traditional Chinese medicine toprohibit other beta use of drugs other than the beta2receptor agonist, antihistamines,desensitization therapy, with the function of relieving asthma. Observation time was10days, began to use1,3,5,6,10days to symptom score, PEF score, curative effect evaluation,safety evaluation and treatment costs respectively in the treatment.ResultThe two groups after treatment, cough score decreased from first days, starting thedrug control group and the experimental group compared with the two groups havestatistical significance, cough scores will be the difference between (P<0.05).In the controlgroup tenth and experimental group sixth days, children’s cough symptoms disappeared, noeffects on learning and sleep. The children in the two groups after treatment, PEF scorewere decreased, but the difference was not statistically significant between the two groups(P>0.05).Experimental group of1patients using Amie Di appeared after a red rash and asmall amount of simplex. Disable Amie Di after the rash and simplex gradually disappear.The control group cough duration and time of hospitalization were test group leader, tospend more, the difference was statistically significant (P<0.05).Conclusion1cough variant asthma persistent airway inflammation and airwayhyperresponsiveness, the principle of the treatment of bronchial asthma can achieve betterefficacy.2Beta2agonists are effective bronchodilators, including short-and long-acting,wherein the short-acting β2receptor agonists are the most effective bronchodilators. 3Amie Di more convenient, effective, reduce the children inhaled and oral drug pain,reduce the course of treatment and treatment costs, is worth the clinical promotion, reducethe possibility of becoming typical bronchial asthma in children.