The Study Of The Genital Tract Infections Impact On The Perinatal Outcome

Objective:To study the characteristics of pregnancy reproductive tract infection, and investigatethe relationship between reproductive tract infection and its intervention measures and thepregnancy outcome, so as to provide experience for the prevention and control ofpregnancy reproductive tract infections, promote maternal and child healthy, and improvethe quality of birth.Methods:Selected sevral pregnancy women about6-36weeks pregnant from March2012toFebruary2013in Yancheng Maternal and Child Care Service Centre, who were given aseries examination, including bacterial infection examination, candida, trichomoniasis,chlamydia, mycoplasma, neisseria gonorrhoeae genital tract infectious diseases. UsingSPSS17.0statistical software for statistical analysis, analysis on the types and distributioncharacteristics of reproductive tract infections among different pregnant time and differentage. According to the pregnant time and their requestments, they were divided into twogroups, treatment group and non-treatment group. Treatment group were givenanti-infection treatment according to the check results, the intervention treatment measuresand its treatment effect and safety would be recorded. Non-treatment group were not givenany treatments. Track the pregnancy outcome of all selected pregnant women,investigation the relationship of reproductive tract infection, different infection types andthe pregnancy outcome. Results:1.The characteristics of pregnancy reproductive tract infectionIn this study,1863cases were given the infection examination, the results shows that1078cases were no infection (non-infection group), accounting for57.86%, and785caseswere reproductive tract infection(infection group), accounting for42.14%. There were nosignificant difference of age, pregnant times, abortion times between infected group andnon-infected group. There’s not statistically significant.The incidence of bacterial vaginal disease, trichomoniasis, mycoplasma, chlamydia,candida, neisseria gonorrhoeae, beta hemolytic streptococcus infection was11%、2.31%、8.91%、4.03%、9.34%、1.45%、5.10%. The infected distribution was that bacterial vaginaldisease, trichomoniasis, mycoplasma, chlamydia, candida, neisseria gonorrhoeae, betahemolytic streptococcus infection, their proportion of total infected diseases were205(26.11%)、43(5.48%)、166(21.15%)、75(9.55%)、174(22.17%)、27(3.44%)、95(12.10%).2. The characteristics of pregnancy reproductive tract infection in different pregnancytimePregnant early infection were297cases, accounting for37.83%; Mid pregnancypatients were250cases, accounting for31.85%; Late pregnancy were238cases,accounting for30.32%. Early pregnancy infection is given priority to bacterial vaginaldisease, candida and Chlamydia infection. The incidence of bacterial vaginal disease inpregnancy is the highest among pregnancy time. Beta hemolytic streptococcus infectionmainly occours in late pregnancy.3. Intervention measures and curative effectIn this study, among785cases of patients,439cases were given treatment astreatment group,346cases without taking the healer as non-treatment group. In treatmentgroup, there were151cases in early pregnancy accounting for19.24%,146cases in midpregnancy accounting for18.60%,142cases in last pregnancy accounting for18.09%. Innon-treatment group, there were146cases in early pregnancy accounting for18.60%,104cases in mid pregnancy accounting for13.25%,96cases in last pregnancy accounting for 12.23%. There was no significant difference between treatment group and non-treatmentgroup, which are comparable. Bacterial infection in the treatment group112cases,25casesof trichomonas vaginitis, mycoplasma infection in85cases, chlamydia infection29cases,vulva vagina candida166cases, neisseria gonorrhoeae22cases. There was no significantdifference in the characteristics of pregnancy reproductive tract infection between thesetwo groups. After careful treatment,209cases in the treatment group was cured (47.61%),157cases were markedly improved (35.76%),52cases were effective (11.85%),21caseswere invalid (4.78%), the general treatment effective rate was83.37%.4.Perinatal outcomeIn these1863cases,562cases had bad perinatal outcome, according to the infectioncharacteristics classified,261cases appear in the non-infected group, incidence was24.21%,301cases appear in the infection group, incidence of38.34%. There wassignificant difference between the two groups（X2=43.065, P<0.05）. According to theintervention measures classified,132cases appear in the treatment group, incidence was30.07%,169cases appear in the non-treatment group, incidence of48.84%. There wassignificant difference between the two groups（X2=28.853, P<0.05）.Conclusion:1. The rate of gestational genital tract infectious disease infection was42.14%, theincidence of bacterial infection is the highest, which is up to26.11%.2. There were no significant difference of age, pregnant times, abortion times betweeninfected group and non-infected group.3. The reproductive tract infection occurs in any pregnancy time, and there was noobvious difference among each pregnancy time, however the characteristics of pregnancyreproductive tract infection in different pregnancy time are different. Early pregnancyinfection is given priority to with bacterial vaginal disease and candida infection, theincidence of bacterial vaginal disease in Mid pregnancy is the lowest among pregnancytime. Beta hemolytic streptococcus infection mainly occours in late pregnancy.4. Reproductive tract infection during pregnancy could get good treatment effect, the total treatment effective rate was83.37%.5. The probability of the occurrence of adverse outcome during pregnancy was30.17%.6. The probability of adverse outcome of reproductive tract infections is significantlyhigher than those non-infected.7. The probability of the occurrence of adverse outcome in treatment group issignificantly lower than that in non-treatment group.