Investigations Of Female Patients With Facial Steroid Dermatitis And Sensitive Skin

【Objective】To understand the morbidity status quo of female patientswith facial steroid dermatitisand sensitive skin through epidemiologicalsurvey. Measuringthe thickness of epidermis and cuticle then comparingwith normal women to understandtheir pathogenesis and to provide anobjective andquantitativeindicator for diagnosis.【Methods】A sample size of32female patients coming per group whowere diagnosed with facial steroid dermatitis or sensitive skin in theDermatology Department of the First Affiliated Hospital of Fujian MedicalUniversity during the period from November to December2013.Then followthese steps.1.Questionnaire,including basic information (aboutage,educationand occupation), personal lifestyle factors, lesionassessment, quality of life index (DLQI) assessment and so on.2. Thethickness of epidermis and cuticlewere measured on the forehead,zygomaticarea, cheek, chin and flexural forearm with confocal laserscanningmicroscope, Vivascope1500.Then the datum of each case groupwascomparedwith50healthy controls.【Results】Through the questionnaire survey and analysis, we foundthat facial steroid dermatitis mostly strikes the middle-aged women whowere less educated,especially housewives. External use drug, putting onmakeup frequently, skin care products and non-professional beautytreatment may be its risk factors. The shapes of skin lesion were variedand it often affected the parts ofinfraorbital, frontal and zygomatic area.While sensitive skin happened more frequently in younger career womenabout30years old.Cosmetics, skin care products, climate change, improper diet may increase its risk. The dermatological manifestation wasfar less diverse, but its affected parts were similar with facial steroiddermatitis. The above both could make patients feel itching,painful,burning, dry and other discomforts. They made the majority of patientssuffer from mental stress.The thickness of epidermis was affected by position as well as age.The thickness of cuticle was influenced by position but age variationwasnot found. Thenormal ranges of differentparts as below, Forehead,8.77-9.06μm；Zygomatic area,8.57-8.87μm；Cheeks,9.00-9.35μm；Chin,9.25-9.60μm；Volar forearm,10.99-11.52μm.We found that thethickness of facial cuticlein each case group was thinner thancontrolgroupwhile the thickness of epidermis decreased only in some age groups.【Conclusions】1.There are different clinical characteristics offemale facial steroid dermatitis and sensitive skin. It is necessary tocarry out some relative health education, life guidance and counselingto combine prevention with treatment.2.The thickness of cuticle can beused as an objective indicator to help diagnosewhen the data is (less than)8.77μm on forehead,8.57μm in zygomatic area,9.00μm in cheeks and9.25μm in chin area.3.Clinical doctorsshould pay attention to help thepatients restore skin barrier function during the course of treatment.