Effects Of Glucose Oxidase On The Performance And The Intestinal Structure Of The Weaning Piglets

In order to study the effect of glucose oxidase on production performance of piglets, and discuss its possible mechanism. This study chooses two experiment aimed to explore the impact of glucose oxidase on production performance, nutrient digestibility and gut microbes and morphological structure of piglets.Experiments 1:To study the effects of glucose oxides (GOD) on growth performances of piglets, one hundred and sixty (10.34±0.35Kg),three-line crossbred (Durocx Landrace* Yorkshire) weaning piglets were randomly divided into 4 treatments, with each treatment represented by 5 replicates of 8 pigs. The pigs in group I fed basal diet, group Ⅱ, Ⅲ and group Ⅳ received basal diet with 100g/t,200g/t and 300g/t GOD, respectively. The experimental period was lasted for 4 weeks in the same breeding management conditions. The results showed that,compared with the control, the highest final weight of the piglets appears in the group IV which received basal diet with 300g/t GOD, reaching 25.93 kg, significantly higher than other groups(p<0.05). Also the highest average daily feed intake comes from the group Ⅳ,reaching 566g/d, significantly higher than other groups (p<0.05),but the difference to the control group is not significant(p>0.05). Also the results showed that the FCR of the group Ⅳ added 300 g/1 glucose oxidase is better than the group Ⅲadded 200g/t. But there is no significant difference on the economic benefits between group Eland groupIV(added GOD with 200g/t and 300g /t).If thinking about the cost of the enzyme and production, the actual 200 g/t added with GOD is more suitable.Experiments 2:Three hundred (8.71±0.13Kg),three-line crossbred (Durocx Landracex Yorkshire) weaning piglets were randomly divided into 3 treatments, with each treatment represented by 5 replicates of 20 pigs. The group Ⅰ fed the basal diet without adding glucose oxidase; the group Ⅱ add 0.1% of chlortetracycline to the basic diet; the group Ⅲ add 200g/t of GOD to the basal diet. The experimental period was lasted for 4 weeks in the same breeding management conditions. The results showed that, compared with the control group I, the ADG of the group Ⅲ which added 200g/T glucose oxidase increased significantly (P<0.05); compared with the group Ⅱ the different was no significant (P> 0.05); The duodenal villus height and villus depth ratio within the height/ duodenal crypt of the group Ⅲ is greater than the groupⅠ, significant difference (P<0.05), the other intestinal segments between the groups were not significantly different (P> 0.05); Digestibility of the diet dry matter and crude protein of the group Ⅱ and Ⅲ was significantly higher than the group Ⅰ (P<0.05); stomach and duodenal pH values decreased significantly in group Ⅲ(P<0.05), and number of E. coli in weaned piglets’ stomach and ileum significantly reduced (P<0.05), the number of lactic acid bacteria significantly increase (P <0.05), but the cecum of each group was not significantly different (P> 0.05). Therefore, the diets which added 200g/t GOD can not only reduce the pH of the piglets stomach and duodenum, but also improve duodenal villus height and feed efficiency of dry matter and crude protein digestion, thereby increasing the production of piglets performance.