Type 2 Diabetic Nephropathy Ⅲ And Ⅳ Of Fiery Pathogenesis

Objective:Investigations by syndromes, analysis in patients with type2diabetic nephropathy in stage III and stage IV of the heat distribution characteristics of symptoms and syndromes, and its correlation with physicochemical properties, explore the heat pathogenesis in diabetic nephropathy patients in stage III, type IV’s main form of expression and its intrinsic link between laboratory measures.Method:Patients who were clinically diagnosed with type-2diabetic nephropathy stage III or stage IV were recruited from Dongzhimen Hospital and other research units during Apr2012to Dec2013. The relevant data will be digitized into the computer, establish a database by the statistical package of SPSS17.0for descriptive analysis and correlation analysis.Results:1. The heat pathogenesis characteristics are prevailly existed in Type2diabetic nephropathy of stage III and stage IV.2. The number of the heat symptoms in stage III patients are significantly more than stage IV patients(P<0.01).The heat performance in stage III patients is severe than stage IV patients (P＜O.05).3.The stomach damp-heat syndrome and the stagnation of liver-fire syndrome are the main syndromes of Type2diabetic nephropathy of stage III and stage IV.4.In stage III patients,the stomach damp-heat syndrome patients with type2diabetic nephropathy compared with non-stomach damp-heat syndrome in patients with high triglycerides (P<0.05), stagnation of liver-fire syndrome of liver depression transforming into fire in course of diabetes than non-patients with short (P<0.05), glycated hemoglobin levels higher than non-patients with deficiency of liver depression transforming into fire (P<0.05). IV National Yang Ming dryness of type2diabetic nephropathy patients with glycosylated hemoglobin levels higher than in patients of non-national Yang Ming dryness (P<0.05) and stomach damp-heat syndrome of patients with non-stomach damp-heat syndrome in patients with a significantly reduced (P<0.01)Conclusion:1. Heat pathogenesis of diabetic nephropathy prevalent in stage III, IV patients.2. Heat pathogenesis may result in shorter course of diabetic nephropathy, heavy glucose and lipid metabolism.