The Impact And Exertion Research Of The Methodology Of Filling Up Genuine Yin To Senil Dementia

With the arrival of aging of the population society, the incidence of senile dementia has been raising significantly. It has brought burdensome incubus to community and family. It has nowadays been the key and difficult points in the medical field, especially inGeriatrics. For a long time, traditional Chinese medicine has accumulated abundant experiences on the prevention and cure for dementia. And it prosses clear dominancy and characteristic to dementia. Senile dementia belongs to "daibing"、"wenchi"、"depression". The site of senile dementia is brain and its base is Kidney. As deficiency of genuine yin is its main pathological basis, replenishing yin is its basic therapy. Statistically, The recipes of replenishing kidney yin is the most in all times recipes of benefit intelligence. Modern research has also proved that replenishing yin has good effects on senile dementia. This method has the function of nourishing the kidney to supplement marrow, strengthening the five zang organs, nourishing yin to dispelling, so it can prevent dementia through invigorating the brain and benefiting intelligence.Because replenishing yin aims principally for dementia whose main pathological factor is deficiency of genuine yin and marrow, applicant indication have to be explicited in clinical treatmentace..Specifically, it is emphasied to apply mainly the salty and cold drugs, ingredient combinate the subduing and settling drugs, nourishing drugs without greasy nature but dispelling function. Senile dementia have long duration of disease. Blood stasis and phlegm are stagnated during the period of senile dementia, so elininating phlegm away and removing blood stasis should be combinated. The drugs of tonifing qi, complimenting the blood, warming yang and regulating qi should be combined properly if the symptoms of qi deficiency, blood deficiency, yang deficiency and qi stagnation.To disscuss the therapeutic mechanism and effect of replenishing genuine yin, many researches have been carried out in the basis of fabricating animal model of scopolamine hydrobromide injection. Consepuentlly, both the recipes composed of replenishing yin and recipes composed of repleshing yin and flushing phlegm away and removing blood stasis drugs have the efficiency of improving memory ability of model rat. Modified sanjiasan has the function of nourishing Kidney to inducing resuscitation. Further studies show that modified sanjiasan can improve VD rat’BMP in serum and cerebrospinal fluid. The model of VD rats were established by bilateral carotide ligation. All in all, replenishing yin has good effect on prevention and cure for senile dementia.