The Clinical Observation Of Common Respiratory Disorders With Hyponatremia

Background:Hyponatremia is one of the common electrolyte disorders indepartment of respiratory medicine, is assumed an important facor ofadverse prognosis. Familiarize and master the diagnosis andprevention of hyponatremia can improve the prognosis of the patient indepartment of respiratory medicine.Objective:To systemic analysis of prevalence， pathogenesis, clinicalcharacteristics and prognostic impact of hyponatremia, and clinicalassociations between hyponatremia and respiratory disorders, in orderto raise awareness of the rights of hyponatremia and guide the clinicaltreatment.Methods:1114cases of patients were analyzed restrospectively, who wereadmitted to the department of respiratory medicine of the BethuneFirst Hospital of Jilin University from January2013to April2013.According to the serum sodium level, the patients were divided intotwo groups normal group and hyponatremia group. Hyponatremiagroup was further divided into mild(130~134mmol/l), moderate（120~129mmol/l）, severe(＜120mmol/l). Collect clinical data，length of stay，clinical indicator，prognosis of the patients，in order toanalyze prevalence and prognosis of hyponatremia，the relationshipbetween hyponatremia and respiratory disorders. Use SPSS21.0statistics software for data analysis. Results:(1)243cases of hyponatremia were found in1114inpatients(21.81%), in which172cases with mild hyponatremia (70.78%) and60cases with moderate hyponatremia(24.69%), severe hyponatremia(4.53%).(2)The age of the patients in the study was between18and97years(mean,59.02±15.29years). The age of patients in the normalgroup was between18and92years(mean,62.35±16.22years).The ageof patients with hyponatremia was between18and92(mean,58.11±14.90). The mean age of hyponatremia group wasremarkably higher than normal group(p＜0.0001).(3)The length ofstay of the patients in the study was between2and21years(mean,6.41±2.59days). The length of stay of patients in the normal group wasbetween2and17years(mean,6.10±2.32days).The length of stay ofpatients with hyponatremia was between18and92(mean,58.11±14.90). Patients admitted with hyponatremia had a longer length ofhospital stay than patients without(p<0.0001).(4)Statistically significantrisk factors for hyponatremia included greater heat rate（85.65:82.77beat/min）, temperature（37.84:36.77℃）, WBC coun（t11.68:6.56×109/L）,BUN（66.46：64.41mmol/l）, and FBG（6.97:5.78mmol/l）, lower DBP（77.61:79.58mmHg）， hemoglobin （121.00:132.98g/l）, albumin（30.35:35.25g/l） and chlorine concentration（93.49:101.92mmol/l）.(5)For patients in the normal group,834cases improved,36unrecovered,1case died, mortality0.11%. For patients with hyponatremia,225casesimproved,15cases unrecovered, and3cases died, mortality1.2%. Patientsadmitted with hyponatremia had a worse outcomes than patients without(p＜0.05).(6)29patients developed hyponatremia during their hospital stay(2.2%).(7) For patients with hospital-acquired hyponatremia,24cases were improved,4cases were unrecovered,1case was died, For patientswithout hospital acquired hyponatremia,810cases were improved,32cases were unrecovered, none was died, Patients with hospital-acquiredhyponatremia had a worse outcomes than patients without（p＜0.05）.Conclusions:(1)Patients in department of respiratory medicine are easylymerged with hyponatremia, in which mild hyponatremia is the mostfrequent form.(2)The patients with hyponatremia have a longer lengthof stay, worse outcomes and higher mortality.(3)Patients indepartment of respiratory medicine can develop hyponatremia duringtheir hospital stay, and patients with hospital-acquired hyponatremiahave a longer length of stay and worse outcomes.(4) Elderly patientsare always combined with hyonatremia, and the prognosis in elderlypatients with hyponatremia is poor.