Clinical Observation Of Ultramicro Modified Zeng Ye Decoction In Treating Slow-transit Constipation (Yin Deficiency And Intestinal Dryness Syndrome)

Objective:To explore the curative effect and estimate safety of ultramicro modified zeng ye decoction in treating slow-transit constipation(yin deficiency and intestinal dryness syndrome).Methods:Patients with slow-transit constipation(yin deficiency and intestinal dryness syndrome) from the outpatient of digestive department in The First Hospital of Hunan University of Chinese Medicine from2013.1-2013.12were randomly divided into ultramicro modified zeng ye decoction treatment group(30cases) and maren capsule control group(30cases) with a treatment course of4weeks for both groups. Patients’ symptoms and signs, traditional Chinese medicine symdromes, colon transmission test were observed and compared before and after treatment.Results:The total effective rates in treatment group and control group were86.67%and73.33%respectively, there was a significant difference between the two groups. It suggested that the curative effect of ultramicro modified zeng ye decoction was superior to maren capsule.There was a significant difference between the two groups in the comparison of onset time of defecation. It suggested that ultramicro modified zeng ye decoction can take effect faster than maren capsule. There was a significant difference between the two groups in the comparison of interval time of defecation. It suggested that ultramicro modified zen ye decoction was superior to maren capsule in reducing interval time of defecation. There was a significant difference between the two groups in the comparison of defecating time. It suggested that ultramicro modified zeng ye decoction was superior to maren capsule in reducing defecating time. The overall recurrence rate of control group was higher than treatment group. However, there was no significant difference between the two groups in prevention of recurrence.There was a significant difference between the two groups in the comparison of residual number of maker at24,48,72hours after taking medicine in colon transmission test. It suggested that these two groups can both develop colon transmission rate.Conclusions:Ultramicro modified zeng ye decoction can improve patients’symptoms and signs and develop colon transmission rate apparently. It has good curative effect, faster onset time and convenient dosing schedule. It is safe and effective prescription in treating slow-transit constipation(yin deficiency and intestinal dryness syndrome).