Clinical Observation On Treating The Type Of Yinxujinkui Of Primary Sjogren’s Syndrome With The Method Of Sheng Jin Run Zao Yaoxue Ways To Improve The Quality Of Life

Objectives:Throuth a multi-center, double blind, placebo-controlled study, make the preliminary evaluation of the clinical efficacy and security of the "Sheng Jin Run Zao Yang Xue"ways for the treatment of the type of Yin Xu Jin Kui of primary Sjogren’s syndrome to improve the quality of life. And explore pSS standardized Chinese medicine treatment and efficacy evaluation program..Methods:The patients who were diognosed pSS in line with the type of Yin Xu Jin Kui were randomly divided into experimental and control groups, They have differently been treated by ShengJinRunZaoyangXue grain and placebo. Then conducted a six-weeks clinical observation to assess symptom scores before and after medication, subjective symptoms of dry, objective examination indicators (salivary flow rate sugar test inspection, the tears flow rate and other laboratory tests), simultaneous detection of adverse drug reactions.Results:1. The number of enrolled patients who meet the program was96(64cases were in the test group,32cases were in the control group), the male to female ratio was1:18, mean age was50years old. a total of23cases withdrew from the study, of which, including6cases of the test group,17patients in the control group. Into the group of patients in the treatment of the former General Information and efficacy related to baseline levels there was no significant difference (P>0.05), comparable.2. The statistical analysis of the results showed that73cases required to complete treatment programs (test group of47patients in the control group,26cases). After the treatment, the patient’s symptom score in the syndrome related inspection, self-assessment integral and dry treatment were improved (P<0.05). Symptom score in the efficacy evaluation, experimental group effectively accounted for63.83%, invalid accounting for36.17%; effective accounting for59.26%of the control group, invalid accounted for40.74%. Credits efficacy evaluation of patient self-assessment test group accounting for78.72%effective, ineffective21.28%; effective accounting for69.67%of the control group, invalid accounted for30.33%. The CMH test the efficacy of the two groups, P=0.0110(<0.05) between the two groups, there was significant difference, to show the efficacy of the test group than the control group.3. Respectively, changes were compared in sugar test, saliva flow rate and the tears flow rate checks before and after treatment, the difference before and after the treatment group were statistically significant (P<0.05), salivary flow rate of the control group and the tears rate treatment no difference before and after (>0.05). Improvement after treatment of the two groups of the three check compare found only sugar tests to improve the situation between the two groups was statistically significant (P<0.05).4Adverse events in trials during the test group and the control group are similar, not statistically significant. Students body fluid nourishing particles cause adverse reactions such as diarrhea, but patients can tolerate no other adverse reactions, so security is high.Conclusion:Health and body fluid nourishing particles can improve the patient’s symptoms of dry, reduce the pressure of life caused to improve the quality of life of Chinese medicine granules are easy to take a good prospect of application in the pace of life in modern society, it is worth in the Community promotion.