| Objective：To investigate the influence of phacoemulsification oncorneal endothelial cells in diabetic cataract patients and diabetic cataractpatients with hypertension.Methods：Phacoemulsification were performed on38patients withdiabetic cataract (42eyes, Diabetes group),40patients with diabeticcataract as well as hypertension (44eyes, Hypertension group), and40patients with senile cataract (48eyes, Control group). The endothelial celldensity (ECD), average cell area, variation in size of endothelial cell (CV)and percentage of hexagonal cell were measured preoperatively and at1week and1month postoperatively applying by specular microscope.Results：1. The endothelial cell density reduced and the average cell areaIncreased in diabetes group and hypertension group compared to controlgroup preoperatively. A significant decrease in percentage of hexagonalcells and a significant increase in variation in size of endothelial cell wereseen in diabetes group and hypertension group (P<0.05).2. Compared to the control group, there were significant differences inthese four parameters postoperatively (P<0.05). Meanwhile, there is a significant decrease in percentage of hexagonal cells and a significantincrease in variation in size of endothelial cell were seen in hypertensiongroup, Compared to the diabetes group (P<0.05).3. There was a steady drop in the endothelial density in the groupspostoperatively, with the percentage of endothelial loss in hypertensiongroup was17.09%and15.08%in diabetes group respectively. Compared tothe percentage of endothelial loss was9.92%in control group, there weresignificant loss in the case groups postoperatively.Conclusion: The function of the corneal endothelial cells in diabeticcataract patients was worse than that in senile cataract patients. The cornealendothelium of diabetic patients is more prone to damage fromphacoemulsification. In addition, hypertension will increase the risk ofphacoemulsification in patient with diabetic cataract. |
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