Comparison Of The Effect To Corneal Endothelial Cells After Cataract Surgery: Phacoemulsification Versus Small-Incision Cataract Surgery

Objective To compare the endothelial cell count(ECC),the morphology(coefficient of variation and Hexagonality) of corneal endothelial cells(CECs)and the central corneal thickness(CCT) changes after phacoemulsification versus small-incision cataract surgery(SICS).Materials and Methods Analysis of 200 cases of cataract patients from April 2014 to December 2014 in our hospital, all patients were followed up for at least 6 weeks. The study of 200 patients were randomly divided into two groups, the first group of 100 patients, which male 53 cases(53 eyes), female 47(47 eyes), mean age of 66.7 + 5.6years. All patients accepted phacoemulsification; 100 patients in the second group,which 55 male cases(55 eyes), 45 patients were female(45 eyes), mean age of 68.1 +4.7 years, these patients will accept SICS. The changes of visual acuity, CCT,endothelial cell density(ECD), coefficient of variation(CV) and Hexagonality were compared between the two groups after operation.Results 1, The best corrected visual acuity(BCVA) at 1 weeks and 6 weeks were much better than preoperative,The differences in BCVA before and after surgery were significant in the two groups(P<0.01),there were no statistically significant differences in BCVA between 1 weeks and 6 weeks after surgery( P>0.05).There were no statistically significant differences in BCVA between the two groups in preoperate,1weeks and 6 weeks after surgery(P>0.05).2, CCT was increase in the two groups at 1 weeks after surgery. At 6 weeks,CCT recovered to the preoperative level in the two groups.There was significant difference in the CCT between 1 weeks and preoperativein the two groups(P <0.05),the difference was not statistically significant between 6 weeks and preoperative in the two groups(P >0.05). There was no significant difference between the two groups at 6weeks and preoperative. The difference of CCT was statistically significant at 1weeks after operation between the two groups(P<0.05).3,In phacoemulsification group,the mean preoperative ECD was2553.25±46.60/mm2, 2341.35±58.59/mm2 at 1 weeks after surgery,2334.95±57.76/mm2 at 6 weeks after surgery,The differences in ECD before and after surgery were significant( P<0.01).In SICS group,the mean preoperative ECD was2561.00±46.80/mm2, 2345.15±73.79/mm2 at 1 weeks after surgery,2339.25±51.56/mm2 at 6 weeks after surgery,The differences in ECD before and after surgery were significant(P<0.01).There was no significant difference between 1 weeks and 6 weeks in the two groups( P>0.05).There were no statistically significant differences in ECD between the two groups in preoperate,1 weeks and 6 weeks after surgery(P>0.05).In phacoemulsification group, ECD loss was 211.90±61.30/mm2 at 1weeks after surgery,214.65±65.43/mm2 at 6 weeks after surgery.In SICS group, ECD loss was 215.85±77.76 个/mm2 at 1 weeks after surgery,221.05±85.74 个/mm2 at 6weeks after surgery.There were no statistically significant differences in ECD loss between the two groups at 1 weeks and 6 weeks after surgery(P>0.05).4,There were no statistically significant differences in CV between the two groups in preoperate,1 weeks and 6 weeks after surgery(P>0.05).5,There were no statistically significant differences in Hexagonality between the two groups in preoperate,1 weeks and 6 weeks after surgery(P>0.05).Conclusion 1,Phacoemulsification Versus SICS, there were no statistically significant differences in BCVA between the two groups.2,Phacoemulsification Versus SICS, there were no statistically significant differences between the two groups in the function and morphology of corneal endothelial cell.3,Preoperative examination, fine and skilled operation,careful observation after operation are the key to reduce the loss of CECs in cataract patients.