Clinical Evaluation Of Intermittent Medication Method In Treating60CPID Cases (Humid Heat And Blood Stasis Syndrome)

Objective:To objective evaluation of the efficacy and safety the method of intermittent medication treatment in chronic pelvic inflammatory disease(Humid Heat and Blood Stasis syndrome). Thus to provide an objective test of the research of Chinese medicine treatment of chronic pelvic inflammatory disease, then valid theoretical basis for the clinical use of intermittent medication treatment of other chronic diseases.Methods:Use multi-center, randomized, blinded, parallel controlled trial, Collection of symptoms, signs credits of the treat group and the control group at the corresponding point time.(1)Group:From December2011to April2012, collected60patients which met the inclusion criteria in Gynecology clinic of Teaching Hospital of Chengdu University of T.C.M、Chengdu Intergrated TCM&Western Medicine Hospital and The Affiliated Hospital of Luzhou Medical college, and divided then into2groups randomly, with the treat group contained30cases and the control group also contained30cases.(2) Mesns:Both of the groups were taken the qing shi zhi tong decoction,the treat group took intermittent medication method, it is means that a drug taking two days, three times a day, and the next day continued service, and the control group took traditional medication method, it is means that a drug taking one days, three times a day, continuous medication for eight weeks on the method.(3) Observation:Collect the patient’s TCM syndrome score at the time before treatment2、4、6、8weeks of medication and one month after discontinuation of cured patients,and to acquisition patients with signs points at the time before treatment4,8weeks of medication and one month after discontinuation of cured patients, also recorded the laboratory parameters before and after eight weeks medication. Results:(1) After treatment, the total points、TCM syndrome score、Signs points were significantly improved of the treatment group and the control group(P<0.05),there is no significant differences between then.(P>0.05);(2) The markedly effective rate of the treatment group is96.66%, the control group is96.67%,there is no significant differences between then.(P>0.05);(3) In the aspect of safety, the two groups had no obvious changes of blood routine, urine routine, ECG and the function of the liver and kidney.And the adverse Gastrointestinal reactions of the treatment group compared with the control group is significantly reduced.Conclusion:Intermittent medication having the same therapeutic effect as with conventional medication,and it is reduced the economic burden of patients, Saving medicines resources, Reduced the gastrointestinal side effects, may try to clinical use.