The Relationship Between Ureaplasma Urealyticum, Chlamydia Trachomatis Infection, Aerobic Bacterium Changes And Chinese Medical Symptom Of Chronic Pelvic Inflammatory Disease

Objective: To explore whether differences of distribution of cervix of secretion ureap lasmaurealyticum(UU),chlamydia trachomatis (CT )and Marginal bacterial community exist in the patients with damp-heat syndrome (DHS),Qi stagnation and blood stasis syndrome(QSBSS) and Qi asthenia and blood stasis syndrome( QABSS) in chronic pelvic inflammatory disease (CPID). Methods: We surveyed 210 cases from outpatients and inpatients with CPID ,including 98 DHS cases,66 QSBSS cases and 46 QABSS cases .The 210 specimens of secretion of cervix were taken and carried on UU and CT examination. The 210 specimens of secretion of cervix were carried on the marginal bacteria colony's examination. Results: (1).Among 210 observation cases of CPID,the rate of positive effect in UU was 57.14% (120/ 210),in CT was 5.71%(12/ 210) and in Aerobic bacterium was 69.05%(145/210). (2)There were significant differences between UU infected and Marginal bacterial community distribution among the group of DHS,QSBSS and QABSS in CPID.We found that there were significant differences between UU infected and Marginal bacterial community distribution between the group of DHS and QSBSS in CPID.there were distinct differences of UU infect and Marginal bacterial community distribution between the group of DHS and QABSS in CPID.There were no significant differences of UU infect and Marginal bacterial community distribution between the group of QSBSS and QABSS in CPID. (3).The predominating population in the CPID with DHS,CPID with QSBSS CPID and CPID with QSBSS were mainly G+germs,up to 76.55% of total germ population. The ratio of different germs in these G+germs was as follows:Staphylococcus epidermidis was 33.79%,E.faecal was 28.97%. The G-germs in predominating population includes E. coli,up to 17.24%. Conclusion: UU,CT and Aerobic bacterium may be pathogenic factors of CPID and may give play to synergetic action in CPID. The predominating population in the CPID with DHS,CPID with QSBSS CPID and CPID with QSBSS were Staphylococcus and E. coli,which suggested that the predominating population of patients with CPID has changed. The DHS in CPID was related to disquilibrium of the flora. There was a degree of similarity between Reproductive tract micro-ecology theory and the knowledge of DHS gynecology in physiology and pathology,the mechanism of Reproductive tract micro-ecology producing disease is that the balance of Reproductive tract microecosystem turn into unbalance,analogy to changing from healthy qi to pathogenic factors in TCM. In a broad sense,"prosperous healthy qi"means balance of microecosystem,"prosperous pathogen"means unbalance of microecosystem.There are two factors Zheng and Xie in the Pathogenicity of damp-heat .when diseases are present by pathogenic damp-heat including exogenous and endogenous,the balance of microecosystem will be destroyed in genital tract.