| Purpose To review our experience of treating38neonates with gastricperforation over18years and to evaluate possible prognostic factor.Methods We retrospectively analyzed38patients with neonatal gastricperforation over18-year period. Noting gender, weight, gestational age,associated anomalies, clinical outcome, type of operation.Result There were25boys and13girls with a mean birth-weight andgestational age of2309g and82.68hours,29of them were premature，30ofthem abnormal APGAR score.30infants had associated problems includingrespiratory distress syndrome, Low Response, vomiting, low temperatureand so on, and16of them had rescue measure. Most of patients hadassociated problem, the most one is pneumonia(71.05%). Mortality rate was23.68%.Gastric perforation with necrosis is worst, Mortality rate was35.71%.All patients with stomach perforation were treated by surgicaloperation.10cases were died postoperatively. Prognosis of gastricperforation associated with gender (P <0.05)、APGAR score（P<0.05）.Prenatal factors associated with neonatal gastric perforation disease, Unclearfor prognosis related (P>0.05). Gestational age, birth weight and gastric perforation neonatal prognosis cannot be clear correlations (P gestational age>0.05, P>0.05).Conclusion This study show that the major factor of neonate’s gastricperforation:1)Hypoxic-ischemic.2)Infection.3)Dysplasia congenitalgastric wall muscle layer.4)Merger of the digestive tract malformation.theprognosis factor of neonate:1)gender2)Apgar scoring3)surgical method andpostoperative management4)Weight of the neonate,wheather prematurebirth or not,prenatal factors and complication are relate to prognosis,but wecan,t clear their relation.Operation method is Surgical repair of gastricperforation or Surgical repair of gastric perforation+Gastrostomy. |
PDF Full Text Request