Meta Analysis Of Comparison Between Sleeve Gastrectomy And Other Surgical Methods About Asian Weight Loss Surgery

Objectives：This article is to analyze and evaluate thesafety and efficacy of sleeve gastrectomy and other surgeries operated inAsian obesities.Method: Electronic searches was applied for the Englishliteratures from PubMed from2000to2013, Chinese and Englishliteratures from WANFANG Database and Chinese Scientific JournalsDatabase of VIP, as well as literatures from Clinical Trail and Chineseclinical trial registration. Manual searching was also applied for somerelevant journals. Weight loss index was observed in12th week,26thweek and52th week after surgery and postoperative adverse reactionsshould be studied in randomized controlled trials when some operationmethods were finished, including laparoscopic sleeve gastrectomysurgery, laparoscopic gastric bypass surgery and laparoscopic duodenaljejunal bypass surgery, as well as laparoscopic gastric bypass. Finally,statistical analysis was operated by RevMan5.1version of CochraneCollaboration software.Results: We found that there was no significant difference between BMIvalues of sleeve gastrectomy group and control group before operation (p=0.40). And there was either no significant difference between BMI level reduction in12th week of sleeve gastrectomy group and other surgicalmethods (P=0.56), while HbA1c level reduction of sleeve gastrectomygroup was significantly lower than that of other surgical groups(p<0.00001) and sleeve gastric surgery was superior to other surgicalprocedures in the aspect of adverse reactions (P <0.0001), without anysignificant difference in the incidence of hypoglycemic events. It wasalso demonstrated BMI level reduction in26th week from sleevegastrectomy group was significantly better than the that from othergroups (P <0.00001), while HbA1c level reduction of sleeve gastrectomygroup was significantly lower than that of other surgical groups(p<0.00001) and sleeve gastric surgery was superior to other surgicalprocedures in the aspect of adverse reactions (P=0.0001), without anysignificant difference in the incidence of hypoglycemic events. It wasalso demonstrated BMI level reduction in52th week from sleevegastrectomy group was significantly better than the that from othergroups (P <0.00001), while HbA1c level reduction of sleeve gastrectomygroup was significantly lower than that of other surgical groups(p<0.00001) and sleeve gastric surgery was superior to other surgicalprocedures in the aspect of adverse reactions (P=0.0001), without anysignificant difference in the incidence of hypoglycemic events.However, other surgical adverse reactions could also be improved aftercertain intervention. Death and other serious adverse reactions were not found in all studies.Conclusions: Sleeve gastrectomy is more securecompared wiht other weight loss surgery, and weight loss effect of sleevegastrectomy in26th week has obvious advantages that from othersurgeries.