Investigation Of Pollution And Health Risk Assessment On Plasticizers In Source And Drinking Water Of Hefei

Objective To investigate the health risk to human beings caused BPs and PAEs insource and drinking water of Hefei.Methods⑴To establish an analytical method for determination of three BPs in waterby ultra performance liquid chromatography-tandem mass spectrometry（SPE-UPLC/MS/MS）,and solid-phase extraction-gas chromatography/massspectrometry （SPE-GC/MS）method for the determination of seven PAEs;The bestconditions for solid phase extraction、chromatography and mass spectrometry wereinvestigated through some programs;⑵The water samples were collected thesource,finished and tap water monitored for one year from the third and the sixthwaterworks of Hefei in different water periods, which include common period, wetperiod and dry period;⑶According to the detection results,used the health riskassessment model recommended by US EPA to evaluate quantitatively of differentgender groups carcinogenic and non-carcinogenic risk through the oral route.Results⑴The3BPs and7PAEs in water were determined by SPE-UPLC/MS/MSand SPE-GC/MS method, respectively.In the1¹00μg/L and0.01¹0.0mg/Lconcentration range with good linear relationship, the correlation coefficient is greaterthan0.9985.For BPs and PAEs, the minimum detectable concentration of were0.75¹.00ng/L and1.50⁹.40ng/L, recovery rate were87.0¹06.9%and84.0¹14.2%, RSDwere1.6³.7%and1.7⁴.2%, respectively.⑵In all samples, BPA,DEHP, DBP,DIBP, DMP,DEP could be detected.For the third and sixth waterworks,the contents of BPA and PAEs in the source water were8.57～15.70ng/L,2.73～8.14μg/L, finishedwater were nd～2.74ng/L,1.91～5.06μg/L and tap water were1.03～3.01ng/L,2.04～6.59μg/L, which all met the National Standards for source and drinking.⑶DEHP andDIBP were the major pollutants, which take45.69%and29.36%in the thirdwaterworks，44.23%and31.44%in the sixth waterworks respectively on average.⑷During different water periods,there was no obvious difference for the plasticizercomponents.The contamination level of different compounds showed differentdistribution characteristics，for BPA was dry period>common period>wet period,forΣPAEs was wet period>dry period>common period.⑸Total removal rate of the thirdand sixth waterworks through the water purification process on plasticizer were42.53%and44.96%, respectively.The removal rate of BPA from the third waterworks werehigher than the sixth waterworks（P<0.05）.⑹The concentrations of BPA, DBP andDEHP in tap water of the third waterworks increased than the finished water, anincrease of66.22%,16.26%and5.96%, the contents of BPA and DBP elevated slightlywith the pipe network distance increased. The each detected target compounds in the tapwater of the sixth waterworks has increased, mainly to DBP, DEHP and BPA, anincrease of63.29%,18.09%and9.83%, and increased with the pipe network distance,but the other PAEs had no significant change in the trend.⑺BPA and PAEs inthe source and drinking water due to the carcinogenic risk from10^-7to10^-5,non-carcinogenic risk of10-3.⑻Carcinogenic and non-carcinogenic risk mainlycame from the DEHP,which had100%and93.11%.⑼The carcinogenic andnon-carcinogenic risk of finished water dropped by30.19%and23.35%for the thirdwaterworks,36.16%and29.00%for the sixth waterworks than the source water.⑽The carcinogenic and non-carcinogenic risk of the tap water was slightly higher than thefinished water, the average growth rate was6.10%and6.46%for the thirdwaterworks,18.40%and and17.74%for the sixth waterworks,respectively. Conclusion⑴The source and drinking water had been polluted by PAEs and DEHAin different levels, the detection concentration all met the current national standard.⑵The conventional and pre-oxidation on water purification process removing of BPA andPAEs was limited,which was recommended that research need to be carried out onremoval of BPA and PAEs;⑶The carcinogenic risk and non-carcinogenic risk wasacceptable by the preliminary assessment,which does not produce significant healthhazards on the adult;⑷Reduce or eliminate the pollution of the source protection areafrom the industrial wastewater and domestic sewage discharge, decreasing the potentialrisks of plasticizer such as DEHP contamination in drinking water.