The Study On Surgery Vision Improvement Of A Novel Sheath For Flexible Cystocopy And Its Safety Evaluation

Objective:To evaluate the effectiveness of NCIS (novel continuous irrigation sheath) on improvingthe vision of flexible cystoscope under gross hematuria, and to investigate whether NCISincrease the discomfort of patients.Methods:The structures and operating procedures of NCIS were briefly introduced. In vitro, a modeland a trial were designed to quantitatively evaluate the effectiveness of NCIS. The trial wasdivided into two parts: the static trial and dynamic trial, the main difference of which iswhether there is continuous hemorrhage. There were three levels of the irrigation condition:no irrigation (group1), continuous irrigation without outflow of water (group2) andcontinuous irrigation with outflow of water (group3). Flexible cystoscopy were conductedunder different conditions and repeated in each model, the main outcome measures FFCV(field of flexible cystoscope’s vision) and DFC (definition of pictures taken by the flexiblecystoscope) were measured at30s,60s,90s and120s. And to investigate whether NCISincrease discomfort,36patients were randomized into two groups: flexible cystoscopywith or without NCIS.Results:Compared with group1and group2, FFCV and DFC were significantly increased in group3in the two models, except that FFCV is not significantly increased compared with group2in the static model. And there was no significant difference in pain score between thepatients accepting flexible cystoscopy with or without NCIS.Conclusion:NCIS can effectively improve the vision of flexible cystoscope and not increase thediscomfort of patients.