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Clinical Observations Of Percutaneous Kyphoplasty For Osteoporotic Vertebral Compression Fractures At Different Operation Times

Posted on:2014-08-02Degree:MasterType:Thesis
Country:ChinaCandidate:N W YaoFull Text:PDF
GTID:2254330398954146Subject:Fractures of TCM science
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Objective:A retrospective analysis of outcomes of thoracolumbar osteoporotic vertebral body compression fractures (OVCFs) suffered Percutaneous kyphoplasty (PKP) treatments at different operation times after injuries in patients. Find out the affects to the outcomes of PKP and the influences of the treatment for OVCFs.Methods:At Wuhan General Hospital of Guangzhou Military Command,from2010January1to January30,2012, there are73patients who suffered from OVCFs at certain times,and they are admitted to be the objects of our reseach. All of them underataken the operation of PKP treatment at different times after injuried.28patients who accepted PKP treatment within one week after injuries include were considered as A group, with total of32vertebral body damaged;45patients who undertake PKP surgery delayed more than four weeks were regarded as group B, with total of57vertebral body damaged. Preoperative average VAS scores for all patients of group A were (7.4±1.3) points, Cobb Angle (22.7±3.8)°, fanterior margin of the damaged vertebral average height was (14.3±2.5) mm; Preoperative average VAS scores for all patients of group B were (6.6±1.1), Cobb Angle (24.2±4.8)°, fanterior margin of average height (13.5±3.6) mm. Compare the outcomes of the two groups preoperation, postoperation and postoperative follow-up of12months.Results:All patients were successfully undertaken surgery. Patients of group A:the amount of each vertebral body bone cement injection was average (5.2±1.3) ml, bone cement leakage occurred in5cases, of rate15.6%(5cases in32cases). When getting of the hospital, patients’average VAS score was (2.4±0.8), improved by (78.5±12.1)%; Cobb Angle was (10.6±2.7)°, improved by (51.1±9.2)%; average hight of fanterior edge was (21.6±2.7) mm, improved by (72.6±6.4)%. After postoperative following-up of12months, VAS score was (1.4±0.5) point. Patients of group B:the amount of each vertebral body bone cement injection was average (3.6±0.9)ml, bone cement leakage occurred in3cases, of rate5.3%(3cases in57cases). When getting of the hospital, patients’average VAS score was (2.2±0.9), improved by (54.5±10.6)%; Cobb Angle was (13.9±5.3)°, improved by (46.1±9.2)%; average hight of fanterior edge was (19.8±3.1) mm, improved by (49.5±5.1)%. After postoperative following-up of12months, VAS score was (1.6±0.4) point. During the postoperative follow-up of12months, there is only2case that again suffered from vertebral refracture in group A, and there are no significant changes in fanterior edge height and Cobb Angle in the rest cases. For all patients,the average vertebral bone cement volume was positively related to rate of improvement of Cobb angle(R=0.54,P<0.01). Compared two groups’ result, the improvement rates of VAS, Cobb Angle and fanterior edge hight were higher than those in group B (P<0.05). Bone cement leakage rate in group B was lower than those of group A. Postoperative VAS scores recorded after following-up12months in both two groups have no significant difference (P>0.05).Conclusion:PKP is an effective method of treatment for OVCFs, and earlier surgical treatment after injuries can obviously alleviate patients’pain, restore vertebral body shape better, but the bone cement leakage rate is higher. Delayed surgery can decrease the leakage of bone cement, and the long-term clinical effect is also satisfied.
Keywords/Search Tags:Percutaneous kyphoplasty, clinical observation, different operation times, osteoporotic vertebralcompression fractures
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