Clinical Analysis Of26Cases Of Cervical Adenocarcinoma

Objective: To investigate the characteristics of clinical and the methods ofdiagnosis and treatment in patients with the cervical adenocarcinoma.Methods: The clinical data of26patients with cervical adenocarcinoma admittedto our hospital from2002.1to2011.12were analyzed retrospectively,carried on thedatabase establishment and statistically analysis by SPSS17.0software.Results:1、The age distribution of patients：the whole group is form31to35years.The age of10patients in2002.1～2006.12concentrate on50~60years,and the age of16patients in2007.1～2011.12concentrate on30~40years.2、Clinical manifestation：In the group16Patients diagnosed Ⅰ～Ⅱastage, there are11(68.75%) cases whoseclinical manifestation is contact hemorrhages. There are7cases(70%)cases in the other10patients diagnosed Ⅱb～Ⅳ stage whose clinical manifestation is irregularbleeding.Comparing the two groups, P<0.05, the differences has statistically significant,it suggests that the clinical manifestation of contact hemorrhages in the early stage forcervical adenocarcinoma diagnosis has more clinical significance, the clinicalmanifestations of irregular bleeding for later stage has more significance. There are8(50%) cases inⅠ～Ⅱastage whose macroscopic type is hypertrophy type.There are8(80%)cases in the group B whose macroscopictype is cauliflower-like type.Comparing the two groups with hypertrophy type andcauliflower-like type,P<0.05,the differences has statistically significant, it suggests thatthe proportion of exogenous type in the early group higher than the later group,then theproportion of cauliflower-like type in the later group higher than the early group.3、Tumor Markers：In the whole group,there are10(41.7%) cases with positive reaction inthe test of serum CA125,8(34.8%) cases with positive reaction in the test of serumCA199,15(75%) cases with positive reaction in the test of serum CA125combinationedwith serum CA199. Comparing the positive rate with the test of serum CA125 combinationed with serum CA199and the test of serum CA125or serum CA199,P<0.05,the differences has statistically significant, it suggests that the joint detection hasthe higher Sensitivity points.4、radiology examine: In the whole group,4cases have theliquid loading in uterine cavity, the depth is3mm、29mm、38mm and60mm.They are allpostmenopausal persons,while two persons have thick endometrium.5、Pathologicalexamination：There are24(96%)cases in25persons were diagnosed definitely beforeoperation.6、Treatment：There are7(87.5%) cases inⅠ～Ⅰb1stage accepted radicalhysterectomy of cervical adenocarcinoma.4cases in Ⅰb2stage accepted radicalhysterectomy after neoadjuvant chemotherapy, while2cases adoptedradio-chemotherapy after radical hysterectomy.2cases in Ⅱbstage adoptedradio-chemotherapy and radical hysterectomy after neoadjuvant chemotherapy, while2cases accepted radical hysterectomy and radio-chemotherapy,2casesradio-chemotherapy. cases inⅢb～Ⅳstage accepted radio-chemotherapy.Conclusion:1、The incidence of cervical adenocarcinoma appears younger trend;2、Contact hemorrhages and hypertrophy cervix are the main clinical manifestations of the early cervical adenocarcinoma; irregular bleeding and cauliflower-like cervix are the main clinical manifestations of the later cervical adenocarcinoma.3、The joint detection of serum CA125and serum CA199has the higher Sensitivity points.4、Regard to liquid loading in uterine cavity,we have to conside the possible of cervical adenocarcinoma.