The Clinical Significance Of Procalcitonin, C-reactive Protein, White Blood Cell And The Percentage Of Neutrophile Granulocyte In Chronic Pneumonia

Objective: To investigate the change and the clinical significance of procalcitonin(PCT), C-reactive protein (CRP), white blood cell (WBC) and the percentage ofneutrophile granulocyte (N%) in patients with chronic pneumonia.Methods:113subjects from Fujian Medical University Union Hospital were enrolledbetween January2012to December2012, including38cases of chronic pneumoniagroup,48cases of acute or subacute pneumonia group and27cases of control group.The blood routine examination, the serum PCT and CRP were tested in the nextmorning after admission to hospital. The date of sex, age, and the testing results ofsputum bacterial culture, PCT, CRP, WBC, N%were collected and compared by thestatistical methods.Results:(1) The level of PCT, CRP, WBC, N%were significantly lower in chronicpneumonia group than that in acute or subacute pneumonia group (P<0.05).(2) TheCRP level was significantly higher in chronic pneumonia group than that in controlgroup (P<0.05). There were no significant difference in the level of PCT, WBC, N%between chronic pneumonia group and control group (P>0.05).(3) The level of PCT,CRP, WBC, N%were significantly higher in acute or subacute pneumonia group thanthat in control group (P<0.05).Conclusion: The level of PCT, CRP, WBC and N%were value for differentialdiagnosis between chronic pneumonia and acute pneumonia. The increase of CRPlevel was helpful to clinical diagnosis in chronic pneumonia patients.