Zhang Peiyu Teacher Of Traditional Chinese Medicine Experience For The Treatment Of Peripheral Nerve Toxicity Caused By Chemotherapy

Objective:To summarize Zhangpei Yu,director of chemotherapy-induced peripheral nerve toxicity of knowledge and unique experience of Chinese medicine treatment,provide new ideas for the the TCM understanding and Diagnosis and Treatment of chemotherapy-induced peripheral neurotoxicity.Method:1. Literature retrieval ancient medical home arthralgia(modern scholars multi considered chemotherapy induced peripheral nerve toxicity when in Chinese medicine "arthromyodynia" category.)As well as contemporary physicians the surrounding nerve toxicity new understanding of the relevant expositions,summarizes the ancient physicians onarthralgia disease name, pathogenesis, diagnosis and treatment of knowledge as well as modern physicians on peripheral nerve toxicity of a new understanding and clinical treatment. Out by nearly two years of follow tutor clinic, rounds, listen to the instructor to explain, lectures, summed up the mentor of the disease pathogenesis, disease, disease location, clinical commonly used prescription with the card changes, as well as analysis of commonly used drugs.Conclusion:This literature review found that chemotherapy-induced peripheral neurotoxicity can be attributed to Chinese medicine arthralgia, etiology and pathogenesis, however, are not the same, treatment guidance, but not all adopted. Although experimental studies have confirmed the effectiveness of traditional Chinese medicine for the treatment of this disease, but modern physicians chemotherapy-induced peripheral nerve toxicity TCM etiology and pathogenesis of understanding there is no consensus, let alone diagnosis and treatment.Director Zhangpei Yu in Chinese medicine for the treatment of cancer and side effects of radiotherapy and chemotherapy for nearly three decades, the malignant TCM has many years of clinical experience, especially the head and neck tumors and the prevention and treatment of radiotherapy and chemotherapy toxicity significant effect of chemotherapy prevention and treatment induced peripheral neurotoxicity formed a complete theoretical system. Chemotherapy understanding of the nature:that is "toxic heat".(2)understanding of the pathogenesis, disease, disease location, and disease transmission becomes chemotherapy without a mass change of the outside to the inside of the direct flow injection blood organs, causing damage to the body. Cause a serious deficiency of blood and body fluids, extremities lost in Ruyang business health ruined, cold invasion, Feng Xie, although the lack of Wei Qi, but even more so no camp overcast outdoors camp Yin injury early as Khan The clinical manifestations of numbness in the hands and feet, evil wind, no sweat. The progression of the disease, the evils outside to the inside, cold invade the meridians, resulting in meridian barrier, phlegm and blood stasis. Cold and dampness and phlegm and blood stasis further block the meridians, resulting in the meridians closed block, the patients extremities, numbness, dull pain, and pain as the main performance. Disease to late, liver and kidney deficiency, blood deficiency, the wind cold dampness evil invasion of the body a long time, missed bones become Arthralgia. Patients of the clinical manifestations of the extremities, numbness, dull, heavy pain at the same time. The development of the disease combined with the gradual invasion of the evils in the business health deficiency of blood and body fluids on the basis of process performance for righteousness constantly deficiency evil is real continuous development. Regardless of good and evil are inseparable from the business health, disease location, the late be related to the liver and other organs. The main square in the treatment of early use of Gui Zhi Tang, toxic heat straight into the spleen, damage Spleen, so on the basis of Guizhi soup plus Sijunzitang. Cold outside to the inside, resulting in meridian block barrier, the phlegm network, Huangqi Guizhi Wu Tang main square, plus active effective remedy to cure and Er Chen Tang. The progression of the disease, cold and dampness and phlegm and blood stasis further block the meridians, as a small active Dan the main square, but Fang system Chuan Wu, Aconitum Xin heat of the goods are easy to Shangyin gas consumption, so more with the addition of Siwutang or ShengmaiYin. Disease to late, liver and kidney deficiency, coupled with the invasion of exogenous pathogens, main square to DUHUOJISHENG, liver and kidney tonic and Chief Qufengchushi.Conclusion:Zhangpei Yu, director of chemotherapy-induced peripheral neurotoxicity TCM etiology, pathogenesis, disease, disease location and Differential Treatment formed their own insights and theoretical system achieved remarkable clinical efficacy. Clinical experience have a strong role in guiding and value in use, to provide new ideas for future clinical understanding and Chinese medicine treatment of chemotherapy-induced peripheral neurotoxicity.