Ge Stilbene Hypoglycemic Granule On Type 2 Diabetes Peripheral Vascular Lesion Blood Flow Dynamics, The Research On The Effects Of D - Dimer

Peripheral vascular disease of type2diabetes, as one of the serious complications of the diabetic patients, seriously affects the patient’s ability to work and quality of life. Western medicine to treat this disease is manly using drugs, surgery, interventional treatment, which are very effective, but, There are some limitations. A large number of clinical data shows that Chinese medicine treatment of this disease has certain advantages.Objctjve:Take yi qi huo xue, qing re jie du as the treatment method, take the orally Chinese traditional medicine, Ge qi jiang tang particle, observe it’ s treating effect on Hemodynaraic、 D-dimer of Peripheral vascular disease of type2diabetes. By contrast before and after treatment of the clinical symptoms, the ankle-brachial index, blood glucose, blood lipids, evaluate Ge qi jiang tang particle’s effects on type2diabetes peripheral vascular disease, explore the medicine’s mechanisms. Hope the medicine can provide a new idea or a new method For Chinese medicine treatment of peripheral vascular disease of type2diabetes.Method:60cases of peripheral vascular disease of type2diabetic were randomly divided into two groups, treatment group and control group, each30cases. The two groups all accept a period of2weeks basic treatment (basic treatment including diet, exercise therapy, insulin hypoglycemic therapy). Achieve the target:FBG <7.8mmol/L,P2hBG<11. lmmol/L(upward fluctuations are. not more than15%of the target level).(HbAlc)<7.0%. After the basic treatment, into the experimental observation, the control group receives placebo, treatment group receives Ge qi jiang tang particle, each group take medicine twice daily, once a bag of drugs. The period of the treatment is eight weeks. After the treatment, observe the changes of clinical symptoms, ankle-brachial index, hemodynamics, D-dimer, blood glucose, blood lipids.Result:1. Markedly effective in17cases, effective in10cases, no effective in3cases in the treatment group,The total effective rate is90%, in the control group, the total effective rate is20%. By statistics processing, P<0.05, there is an extreme notable difference.2. Treatment group in improving D-dimer, lower limb blood hemodynamics, clinical symptoms, the ankle-brachial index is significantly better than beforethere is an extreme notable difference (P<0.05).3. Blood glucose、 blood lipids in treatment group are both far belower than before, the difference is remarkable. But, there is no difference on the HbAlc. However, in the control group, only FBG and TG are far belower than before.Conclusion: This project starts with the clinical studies, discusses comprehensively of the pathogenesis and treatment of type2diabetes peripheral vascular disease. Under the guidance of Lou Xien instructor, I sum up the pathogenesis of type2diabetes peripheral vascular disease is Qi xu xue yu、 re du jin yin. On the basis of the application of basic treatment to control the blood glucose of peripheral vascular disease of type2diabetes, treat the disease with Ge qi jiang tang particle can significantly improve the level of lower limb hemodynamic and D-Dimer,and also significantly improve the clinical symptoms, ankle-brachial index. Except that, it can reduce the level of Blood glucose and blood lipids. Studies have shown that, Ge qi jiang tang particle is an effective drug for preventing and treating of peripheral vascular disease of type2diabetes. And don’t find any side effects, it is worth further promotion and application.