Bupleurum Wendan Soup Combined With Omeprazole Clinical Studies For The Treatment Of Gastroesophageal Reflux Disease (Gallbladder Heat To Make The Stomach)

PURPOSEObservation the Bupleurum Wendan soup clinical efficacy for thetreatment of gastroesophageal reflux disease heat lamps Fan Weicertificate.the theoretical analysis the Bupleurum Wendan Decoctiongastroesophageal reflux disease heat lamps Fan Wei certificatemechanism.MTHOD1.The collection of information： Digestive medicinespecialist clinic patients of60patients Hubei ProvinceTraditional Chinese Medicine Hospital from September2010toFebruary2013， and are in line with Western medicinegastroesophageal reflux disease diagnostic criteria and TCM heatlamps Fan Wei certificate standard. Treatment order randomlydivided into two groups（Treatment group and control group）30people. Treatment group ranged in age from18years old to56yearsold. the average age was36.48±3.320years. Control group rangedin age from21years old to60years old， The average age of38.35 ±3.276years. Two groups of patients were statistically analyzedafter， Their age， gender， disease duration， disease severity，syndromes total points do not exist in significant（P>0.05）.2. Treatment： The treatment group and the control group weregiven omeprazole capsules oral（Goods Ming Aoke）. In the abovetreatment，treatment group Bupleurum Wendan soup.The soup ofBupleurum Wendan is the supervisor Professor Hu Yunlian applicationyears experience side，（The prescription were composedwithchaihu10g， fuling30g， fabanxia15g， zhishi10g， zuru15g，chenpi15g，shengjiang10g，baizhu20g，dazao5mei，jineijin15g，duanwalengzi30g，wuzeigu30g）， these drugs Shuijianbi，，a dailyhalf-hour of the morning and evening meal times， each200ml，omeprazole oral， twice daily， each20mg， morning and eveningbefore meals. Patients in both continuous medication for a courseof treatment（six weeks）， and give security observation（such asblood， urine， stool， liver and kidney function， ECG， and otherpossible adverse reactions）and efficacy observation（acid refluxor retrosternal pain， heartburn and other appropriate clinicalsymptoms and signs， clinical total score before and aftertreatment）.3. processing：After the end of a course of treatment， werestatistically analyzed to determine its efficacy. Count data useSPSS13.0statistical software statistics： χ2test， measurementdata using t test， the ranked data with Ridit inspection （ranksum test）Result：1.Two clinical efficacy after treatment：①Treatment group：Six cases were cured，14cases markedly effective in8cases，2 cases， the total effective rate of93.33%.②Control group： Threecases were cured，8cases were markedly effective in11cases，8cases， the total effective rate was73.33%. Clinical cure ratesof the two groups， the treatment group， the total effective ratehigher than that of the control group（P<0.05）.2. Comparison of two groups： Total score of clinicalsymptoms before and after treatment in both groups is moresignificant sexual differences （P<0.05）. But total scoreimprovement of clinical symptoms， the treatment group than thecontrol group（P<0.05）. Acid reflux， chest pain， depression，and other symptoms， the treatment group improved significantly，significantly better than the control group： Early satiety，belching， mouth waiting for the improvement of the symptoms werecomparable. Of Bupleurum Wendan decoction improve clinicalsymptoms， and fewer adverse reactions to treat gastroesophagealreflux disease， worthy of clinical application.Conclusion：This clinical study shows Integrative heat treatment ofgastroesophageal reflux disease gall Fan Wei certificate was betterthan western medicine group to improve the clinical therapeuticeffect. The Bupleurum Wendan soup may have a regulation ofgastrointestinal function， promote gastrointestinal motility，ease gastrointestinal smooth muscle spasm analgesic antispasmodic，inhibition of acid secretion， combined with relevant westernmedicine synergistic enhanced effect from modern pharmacologicalresearch theoretical analysis. The group description of BupleurumWendan soup party meet clinical practice， there is indeed a certaineffect in the treatment of gastroesophageal reflux disease heat lamps Fan Wei card， worth in the clinical application andpromotion.