Clinical Analysis Of153Cases Of Bronchiolitis

Bronchiolitis in infants and young children during common respiratory infectious diseases, the main clinical manifestations of shortness of breath, chest wall depression, expiratory wheezing and so on. The pathogenesis is not yet fully understood, studies suggest that may be related to environmental factors, genetic factors, immune function, and infection is closely related to infections and allergic to participate in the clinical syndrome. Simultaneous oxygen, carbon dioxide retention, sepsis, and certain immune mechanisms leading to metabolism and organ damage, including myocardial cells, liver cell damage, digestive dysfunction and degeneration of brain cell swelling and even necrosis. The bronchiolitis seriously affect the physical and mental health of infants and young children, causing obstruction to the normal growth and development of infants and young children during the, but also created a burden on the family. Epidemiological data show that if there is a clear history of allergy or a history of asthma in children in the family, bronchiolitis after infection, childhood further developed into a significant increase in the likelihood of asthma, diagnosed allergic disease or atopy children with bronchiolitis, after the development of the probability of asthma was significantly increased, if their parents have a history of bronchiolitis or a history of asthma in children with bronchiolitis, the greater the likelihood of recurrent wheezing disorders within the3-year-old. PurposeDepth discussion of the diagnosis and treatment of children with bronchiolitis experience, to further improve the level of understanding, diagnosis and treatment of bronchiolitis.Materials and methodsCollation and collection of January-December2011Zhengzhou University, Third Affiliated Hospital of child medical hospitalization clinical data of153cases of children with bronchiolitis, from the age of onset, seasonal incidence, clinical manifestations, laboratory tests, imaging studiesresults, treatment, therapy and treatment effects were analyzed retrospectively. Application SPSS17.0software for statistical analysis, using X2test for statistical data conducted to a=0.05for the test level.Results153cases of children with bronchiolitis in men and122cases,31females, the male to female ratio of3.9:1; of age January-year-old, less than1year of age in145patients (94.8%). Clinical manifestations are cough, wheezing, fever in59cases (38.6%), dyspnea in24patients (15.7%), lung auscultation could be heard and expiratory wheezes153cases (100%), could be heard and moist rales62cases (40.5%). The pulmonary damage41cases (26.8%).Laboratory tests:153cases of censorship in52cases, sputum culture was positive in22cases (42.3%). Check cardiac enzymes in79cases,28cases of abnormal (35.4%);76cases of liver function tests, liver function abnormalities in27cases (35.5%).Imaging:114cases cameras anteroposterior chest film examination83illustrates the lung markings visible point of16cases patchy,15illustrates full thorax, both lung fields increased permeability investigation chest CT;39cases,31cases of lung markingsthickening, four cases visible point patchy, four cases of the visible lung field transmittance increased six cases of airway remodeling are no obvious abnormalities.Treatment:laboratory tests suggest that33cases of bacterial infection, giving cough and phlegm, asthma and other symptomatic treatment; positive sputum culture results and laboratory tests there are120cases of apparent bacterial infection indicators given antimicrobial agents; enzyme abnormalities28patients with vitamin C or phosphate sodium injection intravenous drip. Abnormal liver function27cases plus hepatoprotective drug intravenously.Outcome:133cases were cured,20cases improved and discharged.ConclusionsAntimicrobial treatment of bronchiolitis applies only to laboratory check for the presence of significant bacterial infection indicators in children;MP-IgM to check the routine examination can be used as bronchiolitis;A higher incidence of obese children with bronchiolitis.