| OBJECTIVE:To explore the effect of alcohol consumption as well as other multiple factors of life behavior style on dyslipidemia in middle-aged men and to provide some scientific suggestions for this group of people.METHODS:221cases and233controls-males, who were aged from30years old to65years old-had been selected with strict accepting criteria from Second Hospital, Shandong University since June2011to June2012. After got subjects’informed consent, we collected baseline data which included general conditions, alcohol consumption conditions, food intake frequences, smoking frequences, physical exercises conditions, and plasma lipid conditions (including TG, TC, LDL-C, HDL-C levels) by questionnaires. Besides, height, weight, blood pressure were also collected. SPSS17.0was used to do data analysis, which included student’s t test, chi-square test, mono-factor analysis and non-conditional logistic regression analysis.Results:The average ages were45.05±9.78years old and43.82±10.77years old of the case group and control group, respectively. Chi-square test indicated that there is no significant difference of educational level, marriage status, and career between case and control group.The drinking level of case group (75.2%) was significantly higher than control group (60.1%). Drinking history of subjects could be classified as less than5yeas,5to10yeas,10to20yeas and more than20years, and case group’s drinking history was significantly higher than control group’s, respectively. So was to average alcohol intake when alcohol intake were classified as Og/d,<25g/d,25-50g/d,>50g/d four groups. And the OR values (95%confidence interval) of the four groups in control group were1.52(0.95,2.42),1.83(0.97,3.46),3.11(1.86,5.24), respectively. The trend chi-square test indicated that the rising trend is of significant difference. High TG group’s drinking rate and the controls’had a significant difference, same to low HDL-C group. No significant difference was found between high TG group’s alcohol intake and low HDL-C group’s. To high TG group, the OR value (95%confidence interval) was increasing with alcohol intake, which were1.98(1.14,3.44),2.79(1.36,5.71),4.37(2.40,7.94), respectively. The chi-value was25.24, and P value was<0.05.We compared high TG group and control group, and found that moderate alcohol consumption rate and higher drinking rate were significantly different with none drinking rate, meanwhile higher drinking rate was significantly different with none drinking rate in high TG group. As well as to low HDL-C group and control group, moderate alcohol consumption rate was significantly different with none drinking rate.Non-conditional logistic analysis indicated that the average physical exercise(thousand steps/day)(OR=0.926,95%CI=0.888-0.966) was a protect factor and the average daily alcohol consumption (g/d)(OR=1.007,95%CI=1.002～1.012) was a risk factor of dyslipidemia.Conclusion:Alcohol consumption may be a risk factor of dyslipidemia in middle-aged men. With the increase in daily alcohol intake, the risk of dyslipidemia was increasing. Excessive drinking could increase TG, and moderate alcohol consumption may decrease the level of HDL-C. The physical exercise (thousand steps/day) was a protect factor and the average daily alcohol consumption was a risk factor of dyslipidemia. Middle-aged men were key objects of prevention and treatment of dyslipidemia. Related governments should strengthen the health management of the group. |
PDF Full Text Request