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The Study On Specifications And Quality Evaluation Criteria Of Atractylodes Lancea

Posted on:2014-02-21Degree:MasterType:Thesis
Country:ChinaCandidate:M CengFull Text:PDF
GTID:2234330398454090Subject:Pharmacy
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Atractylodes lancea including Atractylodes lancea (Thunb.) DC.and Atractylodes Chinensis Koidz., Rhizoma Atractylodis lanceaecalled Atractylodes lancea, perennial herbs of the genus.Warm,bitter taste sweet, non-toxic, into the spleen and stomach, withspleen dampness,expelling wind, eliminating cold.Atractylodeslancea is mainly produced in Jiangsu, Henan,Hubei and other places;Atractylodes Chinensis is mainly produced in Hebei, Shanxi, andso on.Currently,the market of Chinese Herbal pieces is moreconfusing.The classification of Chinese herbal pieces judgments bytraditional experience can not be given or industry classificationstandard and corresponding quality evaluation method, The qualityof Chinese herbal pieces can not make judgments only bytraditionalexperience,such as shape, color, air, taste, should be combine withthe activeingredients, the overall composition and other factorsof Pieces.Atractylodes lancea as the research object in this topic,thesubject must be based on fully respect the traditional gradingmethods,and further fulfilling objective,scientific of modernquality assessment.Through the study pieces specification and quality evaluationstandard of Atractylodes rhizome,formulated product specificati- ons grading methods and quality evaluation standard of theAtractylodes rhizome pieces,Provide scientific basis for therelevant management measures Atractylodes lancea has twotypes,including Atractylodes lancea (Thunb.) DC. and AtractylodesChinensis Koidz. This subject select market liquidity,corporatehigh yield and commonly used in clinical---Atractylodes ChinensisKoidz.as the research object.Collected theoriginal region and nonauthentic producing of Atractylodes lancea,including Jurong,HenanTongbai as Atractylodes lancea original region, Hubei Yingshan,Qichun, Anhui Luan in the main producing areas for Atractylodeslancea.According to the2010edition of “Chinese pharmacopoeia”cut herbs into slices.According to traditional experience and classificationstandard of export commodity,herbs grading determined pieceslevel,compare Pieces shape, color, taste, texture, clarity andotherindicators,find the difference of the sample.Make thepreliminary classification of Pieces through multifactorcomprehensiveanalysisUsing modern scientific methods, based on the2010"Chinesepharmacopoeia" study of moisture, ash, extract, volatile oil,etc.using microscopic identification and TLC method to identifytheherb Pieces,and the active ingredients atractylodin ofAtractylodes rhizome pieces is determined by HPLC,find its internaldifferences.The content of atractylodis have the meaningclassification,will beidentified as the main indicators ofclassification.And further identify sample level.Samples of all the above preliminary classification TLC,HPLCcharacteristic spectrum research, study their similarities and differences in the two spectra.TLC characteristic spectrum observespots number,color depth,similarity as the main examineindex ofHPLC,analysis of the differences between each evel.To furtherverify thepreliminary classification accuracy and regularity.Based on the above results,the specimen finally divided into twolevels:Optimal level and General level.Make the draft of qualitystandards for all levels pieces.This subject research on quality of various specifications ofAtractylodes rhizome pieces,mainly based on the traditionalexperience,combined with modern scientific methods.Formulateclassification specifications and quality standards of Atracty-lodes rhizome pieces.Grading specifications and quality standards of theAtractyodes lancea Pieces provide basis technical support formanagement departments,provide a scientific basis for the clinicaluse of drugs.
Keywords/Search Tags:Atractylodes rhizome pieces, classification, traditional method, modern scientific methods, themethod of quality evaluation standards
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