Clinical Studies On Treating Pelvic Inflammatory Disease Sequelae (Damp-heat Syndrome) With Danqin Granula

Objective：Observation of traditional Chinese medicine Danqin Granula forthe treatment of pelvic inflammatory disease sequelae of damp heatand junction effects, safety, the use of the side for the clinicaltreatment of the disease and provide data to support and scientificbasis.Methods：In strict accordance with the State Food and Drug Administrationissued the Chinese medicine clinical research guidelines(Trial)(2002)[1]on the disease listed in drug research inclusion criteria,exclusion criteria, the selection of the Hospital of Hubei Provincein-patients and out-patients, doctors diagnosed as pelvicinflammatory disease sequelae TCM for heat stasis type80patients,starting from the day of your visit to take the grain, once a bag,three times a day, continuous medication8week for a course (Stopin period). Observed before and after treatment for each patientsymptoms and signs of improvement in the situation as well as vitalsigns, blood, urine, stool routine, fecal occult blood, liver function, kidney function, ECG, cervical vaginal secretions,gynecology B ultrasonic indices.Results：1. Comprehensive comparison of clinical efficacy: Test fivepeople were cured, effective in16people,10were valid, invalidfive people, the total effective rate was86.11%; control group heal3people,14were markedly effective10people,7people, there isalways efficiency is79.41%, no significant difference between thetwo groups (P>0.05).2.The efficacy of TCM syndrome: The experimental group totaleffective rate was72.22%, total effective rate was70.59%in thecontrol group, between the two groups was no significant difference(P>0.05).3.Part efficacy: Before and after treatment, patients withabdominal pain efficacy difference between the experimental group2.44±1.66, the control group was0.89±1.60, a significantdifference (P <0.05) between the two groups; patients before andafter treatment of lumbosacral pain efficacy the difference betweenthe experimental group was2.11±1.25, the control group was2.12±1.29, no significant difference between the two groups (P>0.05).4. Safety evaluation: Two groups of patients during treatmentwere not found adverse reactions and allergies, general inspectionitems (T, P, R, BP), coagulation, urine, stool, liver function,kidney function, ECG data not found with the drug is directlyrelated to clinically significant abnormal changes in bile Qin Shustars pelvic safe, reliable, non-toxic side effects. Conclusion：Danqin Granula treatment of Damp-heat and junction pelvicinflammatory disease sequelae can significantly improve thepatient’s abdominal pain, lumbosacral pain, vaginal dischargevolume, thick yellow, fatigue, sexual intercourse or menstrual painaggravated relevant clinical symptoms and signs, clinicaltheapplication of non-toxic side effects, safe and effective, worthyof clinical application.