The Affect Of Xiaoyanshengji Paste Of The Damp Mixed Hemorrhoids Postoperative Symptoms And SerumInterferon (IFN-γ)

Objective:Investigate the clinical efficacy of xiaoyanshengji cream on damp after mixed hemorrhoids and may affect serum interferon (IFN-y).Methods:Put60met the inclusion criteria damp after mixed hemorrhoids patients were randomly divided into30patients in each treatment group and the control group, according to the random number table. Both groups on the basis of conventional therapy before and after surgery, the treatment group myogenic with anti-inflammatory cream coated wound dressing control group using Vaseline. At postoperative day1,7days,were compared between the two groups wound pain, edema and collected fasting serum, serum interferon (IFN-γ) content, the two groups were compared wound healing time.Results:1. Wound pain, edema Points prompted two groups after7days,14days wound pain, edema contrast have a significant difference (P<0.05). The treatment group than the control group, postoperative day14wound pain, edema contrast there was no significant difference (P>0.05); Treatment group, the average healing time was11.67days, the control group, the average healing time was14.80days, contrast there is a significant difference (P<0.05), the treatment group was significantly better than the control group; The total effect of the treatment group was96.67%, the total effect of the control group was approximately93.33%, P>0.05, no significant difference.2.Serum interferon (IFN-γ):Preoperative no statistically significant differences with the first day after surgery, the serum interferon IFN-γ levels comparable (by t-test, all P>0.05). Preoperative IFN-γ levels after surgery as well as before and after treatment group difference was statistically significant (by t-test, all P <0.05),Analysis of its average number shows that serum interferon IFN-γ levels at first increases and then gradually decreases with the improvement of symptoms of edema pain after surgery.Postoperative7days IFN-γ group comparison P<0.05, both significant difference between the treatment group, IFN-γ levels were lower than those in the control group;3. The course of medication in the treatment group and the control group were not found significant adverse reactions.Conclusion:1. Xiaoyanshengji paste outside for the damp mixed hemorrhoids postoperative, Can effectively relieve pain, edema in the book, Shorten the time of wound healing, promote wound healing, Significant clinical effect, also found no significant adverse reactions.2. The xiaoyanshengji paste may be provided by reducing the serum interferon (IFN-γ) level, In order to achieve the effect of control inflammation, improve symptoms.