Patients With Type2Diabetes Mellitus Blood Sugar And Related Risk Factors And Cognitive Impairment Of The Relationship

Objective:To investigate the relationship between blood sugar control and cognitive impairment in type2diabetic patients,and to analyze other related risk factors influencing cognitive function.to explore the prediction and diagnostic value of cognitive impairment in type2diabetes.Method:We Select129patients with T2DM in outpatient department and physical examination center according to the Mini-Mental State Examination(MMSE) score, T2DM patients were divided into three groups--noncognitive impairment, mild cognitive impairment,and dementia.Each were subdivided into two groups by blood sugar—well-controlled and not well-controlled. T test and x2test was used to the comparation of the followup data for congnitive function,blood pressure(BP), The analysis of Spearman correlation was used influencing factors of MMSE score CMS score and MoCA score, Mca. A P value less than0.05was considered indicative of statistical significance.Result:1. After one year’s followup.,the constituent ratio of blood sugar not well-controlled was significantly lower than well-controlled in the morbidity of CI in the normal group,MCI group and the dementia group.(P<0.05)2. Not well-controlled was significantly lower than well-controlled in the meaningless graph recognitive,portrait feature recall and clinical memory scale (CMS).After one year, not well-controlled’s score of directing memory、ssociative learning、image free recall and MMSE、CMS was significantly lower than well-controlled.To compare before and after followup of well-controlled,only portrait feature recall significantly decreased (P<0.05);while in the group of not well-controlled, MMSE、CMS、directing memory、associative learning、image free recall、meaningless graph recognitive、portrait feature recall were all significantly decreased. 3. After one year’s followup.,the constituent ratio of the group with hypertention was significantly lower than the group without hypertention in the morbidity of CI in the normal group,MCI group and the dementia group.(P<0.05)4. In the first visit the group with hypertention was significantly lower than the group without hypertention in theMMSE andMoCA..(P<0.05)After one year, the group with hypertention was significantly lower than the group without hypertention in theMMSE andMoCA.(P<0.05)After one year,the follow-up cases was significantly lower than the fist cases in theMMSE andMoCA. In the same blood press pressure.(P<0.05)Conclusion:1. Poor control of blood sugar can increase diabetes patients cognitive dysfunction of progress.2. Poor control of blood sugar can make the memory function the scope of the damage significantly increased.3. Diabetes combined with high blood pressure, can further promote aggravating cognitive dysfunction of progress.4. Good blood glucose and blood pressure control can effectively prevent diabetes combined with cognitive dysfunction of progress.