| Objective: In this study based on clinical, through the comparison of type2diabetes (Type2diabetes mellitus, T2DM) in hypertensive patients with glycosylatedhemoglobin Alc(glycated of hemoglobin Alc, HbAlc) and glycosylated serumprotein (glycatedserum serum Protein GSP), it explores the T2DM with the bestindicator of blood glucose monitoring of patients with hypertension for such patients，which seek more reasonable preventive measures and effective way to providescientific and applied to clinical and service.Method:30cases of pure type2diabetic patients were selected according to thestudy’s selection criteria, with hypertension in30cases, collected the clinical data of theselected candidates, determination of HbAlc and GSP and commonly used clinical andbiochemical indicators.In the two groups, measurement data were presented as mean±standard deviation description and count data were used the χ~2test,the normaldistribution of measurement data were taken the t-test and rank sum test for non-normaldistribution of measurement data, the correlation between the index of linear correlationanalysis and multiple linear regression analysis, which were taken SPSS13.0statisticalsoftware analysis to determine the inspection level of P<0.05.Result:(1) Body mass index and triglyceride levels of group A are below group B (P <0.05);High-density lipoprotein level of group A is higher than B group (P <0.05).(2) The detection rate of lipid metabolism disorders in group A is46.67%(14/30)less than76.67%(23/30) in group B (the chi-square=5.71, P <0.05); the detection rate of overweight in group A is16.66%(5/30) less than40.00%(12/30)in group B (thechi-square=4.02, P <0.05); obesity rate in group A is6.67%(2/30) less than26.67%(8/30) in group B (the chi-square=4.32, P <0.05).(3) The detection rate of anemia in group A is10.00%(3/30) less than50.00%(15/30) in group B (the chi-square=11.43, P <0.05); detection rate of hypoalbuminemiain group A is6.67%(2/30) less than10.00%(3/30) in group B (the chi-square=0.22, P>0.05).(4) HbAlc of group A is positively correlated with Hb (r=o.396, p <0.05), GSPand Alb have no correlation (r=-0.037, P>0.05), GSP is positively related to the BUN(r=o.407, P <0.05)and Cr (r=o.379, P <0.05); HbAlc of group B is a positivecorrelation with Hb (r=o.743, P <0.01), GSP and Alb have no correlation (r=0.164, P>0.05).(5) MBG in group A is correlated with HbAlc (r=0.446, P <0.05) and GSP (r=O.949, P <0.01),in group B MBG and HbAlc have no correlation(r=O.247, P>0.05),there is a correlation between MBG and GSP (r=0.808, P <0.01).(6) With linear regression analysis and HbAlc for the dependent variable, asbiochemical indicators for the independent variable, MBG in group A is independentfactors (beta=0.446, P=0.014). Hb in group B is independent factors (beta=0.743, P=0.000). With GSP for the dependent variable, as biochemical index for the independentvariable, MBG in group A is independent factors (beta=0.949, P=0.000). MBG ingroup B is the independent factors (beta=o.808，P=0.000).Conclusion:(1) Detection rate of lipid metabolism disorders, overweight and obese in simpleT2DM patients is lower than T2DM with high blood pressure patients. Need to adjustblood fat, high blood pressure and control weight,which delay the complications ofevents.(2) T2DM with high blood pressure is more likely to merge anemia, which can affectHbAlc test results. (3) Type2diabetes combined with high blood pressure patients are affected byanemia, HbAlc and MBG have no correlation. Anemia is great influence to test of HbAlc,and at the time of the results of the numerical will appear spurious, so to blood sugar testthe appraisal of the GSP is more effective role, for type2diabetes combined withhypertension,GSP is more suitable for a blood sugar evaluation indications. |
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