Clinical Efficacy Of Red Flea Treatment Of Acne

Objective:To observe the effect of red flea side Clarithromycin sustained release tablets, the tanshinone capsule three groups of patients with acne clinical symptoms and skin lesions integral changes, compare the red flea side Clarithromycin sustained-release tablets in the treatment of acne antibacterial efficacy observed red flea treatment of acne indication type and side effects, and provide new clues and ideas for clinical treatment.Materials and Methods:240cases confirmed by hospital dermatology clinic patients with acne vulgaris were randomly divided into three groups:the experimental group and control group A, control group B, n=80cases. According to syndrome differentiation typing in the experimental group:lung by wind-heat type32cases, heat Accumulation34cases, phlegm condensation type14cases,30cases of group A:lung wind-heat control, heat Accumulation37cases, phlegm condensation of13cases, control of33cases of group B: the lung by wind-heat, heat Accumulation29cases, phlegm-condensing18cases. The experimental group of internal medicine red flea side water decoction of a daily200ml/2times/day, essential drugs consisting of:red peony root15g, paeonol 20g, Salvia30g, red flea Hugh15g, the Chuanxiong15g, Angelica Last15g wind15g, the day the small15g, Viola15g, dandelion15g,Forsythia15g, honeysuckle10g. The control group A with oral Clarithromycin Sustained Release Tablets0.5g/times/day. Control group B with oral a tanshinone capsules of1g/times,3times/day. All observed cases medication for three weeks to record medication acne lesions before and after integration, to compare the three groups of patients points change.Observation points:1. Symptom score:including the main symptoms of integral points of this disease, the main symptoms integral refers to the points of acne lesions, disease integral TCM accompanying symptoms and Tongue and Pulse Points. Two. Acne vulgaris lesions Clinical evaluation:healed:N>95%; markedly:70%≤N<95%; effective:50%≤N<70%; invalid:N<50%, or anti-see increased. The skin lesions subsided rate (N)=lesions points a therapy after the lesions points (before treatment)+treatment before skin lesions points×100%.3. Traditional Chinese medicine syndrome of acne vulgaris Clinical evaluation: healed:n≥95%; markedly:70%≤n<95%; effective:50%≤n <70%; invalid:n<50%. TCM Syndrome index (n)=(before treatment points of the pre-treatment score points after treatment)÷×100%Results:1. A. Designate synthetic effect of the experimental group and control group of TCM There was a significant difference (P<0.05, the experimental group and recover from illness a significant rate of81.25%, control group A recover from illness penetrance is71.25%.2. The efficacy of the experimental group and control group B of TCM designate significant difference (P<0.05), the experimental group and recover from illness penetrance is81.25%, control group B recover from illness penetrance is55.00%.3. Control group A and control group B of TCM Syndrome synthetic effect difference (P<0.05), which the control group A recover from illness a significant rate of71.25%, control group B recover from illness a significant rate is55.00%.4. Experimental group and control group A traditional Chinese medicine syndrome lungs by wind-heat type, a significant difference (P<0.05), The experimental group and the lungs through the wind and heat recover from illness penetrance is75.00%, control group A lung by wind and heat recover from illness penetrance is60.00%.5Experimental group and control group A TCM syndromes hot and humid Accumulation Type is a significant sex difference (P <0.05). Experimental group heat Accumulation recover from illness penetrance is82.35%, control group A hot and humid Accumulation Type recover from illness rate is62.17%.6. Designate phlegm. The experimental group and control group A of TCM condensation-type was no significant difference (P>0.05), but efficiency higher than that in control group A, the experimental group phlegm condensation efficiency is85.71%, control group A sputum a wet condensation efficiency is69.23%.7. Experimental group and control group B of TCM Syndrome lung by wind-heat type, significant difference (P<0.05),The experimental group and lung by the wind-heat type recover from illness rate is75.00%, control group B lungs through the wind and heat recover from illness penetrance is54.54%.8. The experimental group and control group B of TCM Syndrome heat Accumulation Type significant difference (P<0.05).The experimental group and hot and humid Accumulation Type recover from illness rate is82.35%, control group B heat Accumulation recover from illness significant rate is68.96%.9. Designate phlegm. The experimental group and control group B of TCM condensation-type was no significant difference (P>0.05), but efficiency higher than that in control group B, the experimental group phlegm condensation efficiency is85.71%, control group B sputum a wet condensation efficiency is55.56%.10. Compared to the experimental group and control group recurrence rate, P<0.05, there are significant differences. The experimental group and control group B, P<0.05, there are significant differences.Conclusion:Internal medicine red flea Treatment of acne efficacy is superior to the tanshinone capsules, for the hot and humid Accumulation Type, lung phlegm condensation type wind-heat type of acne is also effective, the antibacterial efficacy of the treatment of acne is stronger than the sustained release tablets of clarithromycin, which can effectively avoid antibiotic resistance and side effects caused by long-term application, shorten the treatment period, reduce the relapse rate, it is worth further clinical application.