Born Rhubarb Vinegar Retention Enema And Milk Ructose Oral To Hepatic Encephalopathy Curative Effect Observtion

Purpose:Hepatic encephalopathy is a disorder of the central nervous system function mainly by the disturbance of consciousness. The most fundamental cause of acute and chronic liver dysfunction and/or doors-shunt toxic substances from the intestine to the liver detoxify or clear, or directly into the systemic circulation through the collateral circulation bypassing the liver through the blood-brain barrier to reach brain tissue caused by brain dysfunction. Often portosystemic shunt on the basis of acute and chronic liver failure, cirrhosis, spontaneous or caused by human activity. Disease mortality rates were higher, and easy to recurrent. Western medicine on the treatment of hepatic encephalopathy program commonly used are:the removal of incentives to reduce ammonia, nutritional support, cirrhosis, chronic liver failure on the basis of recurrent episodes of hepatic encephalopathy, liver transplantation is often the only effective treatment method. The high cost of liver transplantation and liver source, many patients lost their lives due to the cost or the lack of liver source. In the drug, lactulose due to its anti-endotoxin effect is often used in clinical treatment of hepatic encephalopathy, with a certain drop of ammonia, control or reduce the role of hepatic encephalopathy, but there are higher cost, the effect not significant and long-term side effects of the shortcomings. In recent years, studies have reported more on the application of rhubarb or vinegar enema treatment of hepatic encephalopathy, efficacy, and low-cost, reducing the economic burden of the patients, therefore a certain clinic. This trial will be rhubarb, vinegar enema and lactulose oral in reducing blood ammonia and intestinal PH value, to evaluate efficacy difference, to provide a basis for clinical drugs of choice.Method:Selected cases from the medical treatment center in Wuhan City Chinese and Western combined with liver disease admitted from40patients, the clinical diagnosis of hepatic encephalopathy criteria, were randomly divided into two groups, group treated with Western medicine basis Hugan off ammonia, and supportive treatment. On this basis, the observation group to be rhubarb, vinegar enema Enema:rhubarb30g boiling juice,30%vinegar30ml, total100ml. Take enema100ml body suitable temperature, tube length15-20cm, take hip exalteth10cm bit, slowly inject the enema into the colon and splenic flexure, Zhu Huanzhe right side of the side, so that liquid into the right colon; control The group was treated with oral lactulose. Five days for a course, for a total observation of the three courses. Ammonia (μmol/L) and in vivo PH value of the observed indicators of the course before and after three courses of treatment in order to investigate the evaluation time.Results:1. Efficacy in reducing blood ammonia aspects, the observation group than the control group (P<0.05). 2. The observation group in the acidification of intestinal environmental effects than the control group (P<0.05).3. The observation group in the treatment efficiency is also higher than that in the control group55%of the efficiency of the observation group and control group was40%in the observation group total efficiency of85%in the control group the total efficiency of70%.4. The observation time was15days in the observation group found no significant toxicity, and the control group had one case of serum creatinine increased.Conclusion:The test will be rhubarb vinegar to retain the enema for hepatic encephalopathy with lactulose oral compared to observe the rhubarb, vinegar enema in the course of treatment of hepatic encephalopathy. Belong to study traditional Chinese medicine enema treatment of the disease. Many scholars simple rhubarb enema or pure vinegar enema treatment of hepatic encephalopathy in this area, this test is rhubarb vinegar joint retention enema, oral studies compared with lactulose, effects were observed, was born rhubarb vinegar enema reduction of ammonia and acidification of the intestinal environment is superior to oral lactulose, treatment efficiency and significantly more efficient than oral lactulose is effective, worthy of promotion.