The Relarionship Between C-Reactive Protein And Colon Adenoma

Objective To explore that the relationship to C-creactive protein and the colonic adenoma.Methods From2007July to2010July, in Jilin province the people hospital to selected the implementation of colonoscopy in5315cases of the gastrointestinal tract symptoms to patients and the healthy check-up. Find polyps patients, and the exclusion of various acute and chronic inflammatory reaction, hypertension, heart disease, diabetes, may lead to increased CRP, fasting venous blood collected in serum2ml, then in the colon endoscopic resection of polyps, submission of polyps, for pathological examination was consistent with colonic adenomas pathologic criteria for selected cases; And colonoscopy in normal to healthy people as control group, also in fasting venous blood collected in serum of2ml; determination of CRP value of the sample In the laboratory staff do not know has been detected in samples under conditions. Case1387cases of male and female1415cases).The control group1285cases of male, female1228cases. Through the case control and the method of statistical analysis, compares the control group and the case group between the two groups C-reaction protein concentration are there significant differences.Result There is no difference of CRP among different females in the experimental group (P>0.05); there is significant difference in different males in the experimental group (P<0.05). The differences among the different groups of female and males in the control are not significant (P>0.05).The differences among the different groups of female and males in the experimental and control are significant (P<0.05). Age, sex and the influence of various factors can influence the concentration of CRP.Conclusion CRP in patients of different ages is relative to colon adenoma, it can be used as index of screening for colorectal adenoma, but age、 sex and the influence of various factors can influence the concentration of CRP, there is no specificity.