The Curative Effect Of Salvia Miltioixhiza Injection In The Treatment Of Pulmonary Interstitial Ifbrosis(both Of Lung And Kidney Eficiericy)

Objective:The treatment of salvia miltiorrhiza injection pulmonary fibrosis (lungkidney deficiency of both type) clinical curative effect observation and salvia miltiorrhizain rats injection pulmonary fibrosis model experimental study of impact, this paperdiscusses salvia miltiorrhiza in the treatment of injection pulmonary fibrosis disease in therole.Methods: Patients with pulmonary fibrosis patients were randomized into control andsalvia miltiorrhiza groups, and every24cases. The control group in western medicinetreatment routine treatment method (hormone anti-inflammation, infection, eliminatingphlegm to smooth wheezing (and, oxidation resistance, oxygen therapy and other), danshengroup in western medicine, conventional treatment based on add with intravenous injectionsalvia miltiorrhiza bit, two groups of course are14days, compared with two groups beforeand after treatment between the two groups of traditional Chinese medicine and sicknessintegral, pulmonary function, and pulmonary HRCT, blood gas analysis and relatedindicators, and experimental study in bo to injection salvia miltiorrhiza rats induced withpulmonary fibrosis of the role of salvia miltiorrhiza injection evidence for the curativeeffect of pulmonary fibrosis.Results:1. The clinical research: TCM symptoms integral two groups before andafter treatment with significant difference (P <0.05), two groups between after treatmentwith significant difference (P <0.05); Lung HRCT abnormal image area of two groupsafter treating a significantly reduce before treatment, two groups of treatment is not seenbetween significant difference (P>0.05); Lung function two groups before and after treatment with significant difference (P <0.05), two groups between after treatmentwith significant difference (P <0.05); PaO2two groups before and after treatment withsignificant difference (P <0.05), two groups between after treatment with significantdifference (P <0.05).2. Experimental study: salvia miltiorrhiza group and hormone groupand in the blank group and model group in the lung coefficient, the alveolar inflammation,fibrosis degree was significant difference (P <0.05); Salvia miltiorrhiza group andhormone group in the lung coefficient was significant difference (P <0.05), in alveolarinflammation, fibrosis degree is not seen significant difference (P>0.05).Conclusion: Salvia miltiorrhiza injection glucocorticoid, western medicine combinedroutine therapy for pulmonary fibrosis (lung kidney deficiency of both type) has atherapeutic effect, can assist to improve clinical symptoms, signs, improve FVC, FEV1,DLco and PaO2clinical indicators, the action mechanism may and anti-inflammation,fibrosis and other relevant mechanism.