The Research Of The Relationship Of The Levels Of GLP-1of Serums And Type2Diabetes Occur The Risk Of Cardiovascular

Objective: Study the relationship of the serums GLP-1levels and the risk ofcardiovascular in119cases of type2diabetes.Method：Clinical data of119cases of type2diabetes (height, weight, waistcircumference, hip circumference, waist-hip ratio, blood pressure) and peripheral veinblood samples were collected. Biochemical detections (Triglyceridemia，Cholesterolemia，Low-density lipoprotein，High-density lipoprotein, fasting and2-hour postprandial blood glucose levels, serum insulin and C peptide, glycosylatedhemoglobin) were also collected. Serum GLP-1levels were measured by ELISA.Measurement data using the normality test, normally distributed variables x±s.Non-normal distribution of data expressed as median (min-max). Mean normallydistributed variables between groups were compared using independent samples t test,multiple sets of the mean were compared using one-way ANOVA of statisticalmethods were used to analyze the correlation between serum GLP-1levels andcardiovascular risk in119cases of type2diabetes.Results: According to fasting serum GLP-1the level, the population is divided intofour groups, The results showed that with the fasting GLP-1levels declined,Framingham10-year cardiovascular risk is an increasing trend (p>0.05), fastingGLP-1levels in the lowest group, the Framingham10-year cardiovascular risk scoreis high.Conclusions：Fasting serum GLP-1level and the Framingham10-year cardiovascularrisk showed the trends of Negative correlation.