Clinical Study On Effect Of Nao De Jian Granules On Patients With Acute Cerebral Infarction And HIF-1α And Ang Ⅰ Level In Serum

Objective:To observe the clinical therapeutic effect of nao de jian granules on Patients with Acute Cerebral Infarction and HIF-la and Ang I Level in serumMethods:Forty-two cases suffered from Acute Cerebral Infarction were randomly divided into treatment group of granules added Western medicine treatment and control group of Western medicine treatment. Then changes of symptom physical sign,Neurological deficit recovery efficacy,HIF-1a and Ang I level in serum. Two groups were analyzed before and after treatment.Result:1.Effects of TCM:The effective rate of the treatment group was95.24%. The effective rate of the control group was71.43%.There were significant differences between the two groups(P<0.05).The treatment group made a better than the control group.2. Points of TCM between before the treatment and after the treatment:There were significant differences between the two groups in points of TCM improvements(P<0.05).The treatment group made a better than the control group.3. Effects of Neurological:The effective rate of the treatment group was90.48%. The effective rate of the control group was52.38%.There were significant differences between the two groups(P<0.05).The treatment group made a better than the control group.4.Points of Neurological deficit recovery efficacy before and after the treatment:There were significant differences between the two groups in points of Neurological deficit improvements(P<0.05). The treatment group made a better than the control group.5. Effects of clinical symptoms:The effective rate of the treatment group was71.43%. The effective rate of the control group was38.1%.There were significant differences between the two groups(P<0.05).The treatment group made a better than the control group.6.HIF-1a and Angl level in serum of Two groups Before and after treatment:The HIF-la and Angl level in serum of Two groups were significant different.(P<0.05). The treatment group made a better than the control group.Conclusion:Both method for treating acute cerebral infarction Patient have certain therapeutic effect, but nao de jian granules group treatment made a better effect.