The Clinical Curative Effect Observation Of The Treatment Of Qingfeizhike Decoction On Chronic Cough

Objective:Chronic cough is one of the common diseases of the respiratory system, causing a serious impact on long-term frequent violent coughing of the patient’s life, work and social activities. Because of its complex etiology, clinical chest radiographic findings, no obvious abnormalities of chronic cough, the most easily overlooked by the doctor, resulting in many patients have long been misdiagnosed as chronic bronchitis, extensive use of antibiotic therapy, makes repeated illness and it is irreversible even lead to superinfection, so that not only increases patient costs, but also increased the patient’s mental burden.The clinical study was to use the self side of Qingfeizhike the treatment of chronic cough and phlegm obstruct the pulmonary type, by observing the chronic cough patients taking Qingfeizhike side addition and subtraction before and after treatment, improvement of symptoms, and compared with the control group to explore Qingfei cough side treatment of chronic cough in clinical efficacy and mechanism of action, provide a scientific basis for clinical use.Methods:Choose from January2010to May2011, in Wuhan Hospital of Traditional Chinese Medicine, a total of198cases of hospitalized patients diagnosed as chronic cough, randomly divided into treatment and control groups. Treatment group99cases, male41and female58; average age of62.5±7.4years, the average duration10.75±2.13weeks.The control group of99cases, male43and female56; average age of63.1±7.1years, the average duration11.02±2.05weeks. General information on the two groups were compared, no significant difference (P>0.05) were comparable. Selected patients meet the diagnostic guidelines of the Chinese Society of Respiratory Disease credits asthma study group to develop chronic cough syndrome type with reference to the2002Chinese medical science of TCM Hou diagnostic criteria after detailed history, the system of physical examination, and indicators of laboratory tests. Treatment group were given oral cough Qingfei Decoction and intravenous infusion of Yan Hu Ning (320mg qd), drugs:Scutellaria, gardenia, tuckahoe, cordate houttuynia, Campanulaceae, Fructus aurantii, tangerine peel, method, licorice; control group blood test blood leukocyte to cefmenoxime (2.0mg, qd) intravenous infusion of normal white blood cell to Yanhuning (320mg, qd) intravenous infusion, at the same time I ambroxol (60mg tid) orally. Chi-square analysis was used to compare observations application of statistical software SPSS13.0data processing rate. P<0.05was considered statistically significant.Results:1. The total efficacy of the treatment group35cases cured,39cases markedly effective in21cases,inactive of4cases, the total efficiency of95.96%; control group cured30cases,28cases markedly effective in17cases and inactive of24cases, with a total75.76%. The total effective rate comparison X′-=16.897, P<0.01, the difference of statistical significance, all results show the effect of the treatment group was significantly higher.2. The main symptoms of efficacy were compared before and after treatment The main symptoms of the effects shown in Table4results show that the treatment group compared with the control group cough, expectoration, symptoms were improved in the scoring difference was significant (P<0.05), the comparison of two groups of patients with wheezing, score the difference was not significant (P>0.05).3. adverse reactions observed treatment group a total of99patients during the treatment well tolerated in patients, blood, urine, liver and kidney function did not change significantly, Description Qingfeizhike soup toxic side effects.Conclusion:Clinical trial results showed the Qingfeizhike treatment of chronic cough (phlegm obstruct the lung), with the effect of phlegm Xuanfei cough. On the total effective rate was significantly higher improvement in patients with cough, expectoration symptoms than the control group, compared with the control group, it has better anti-asthmatic effect. And no significant side effects and adverse reactions, clinical dialectical accurate, appropriate compatibility, you can obtain a better therapeutic effect, with broad prospects.