Qingfei Cough Syrups And Children Qingfeizhike Effervescent Quality Standards In Children

The quality standard of "Xiaoerqingfezhike Effervescent Tablet" supported by The Department of Education of zhejiang Province, was studied. It is based Xiaoerqingfezhike syrup. The thesis focuses on both Radix Scutellariae and Bulbus Fritillariae Hupehensis. The major active compounds in the effervescent tablets were determined, which can offer gist for the establishment of the quality standard of Xiaoerqingfezhike Effervescent Tablet.Radix Scutellariae and Bulbus Fritillariae Hupehensis, the major herbs in the Effervescent Tablets, are commonly used Chinese herbal medicines incorporated by Chinese Pharmacopia. Radix Scutellariae, the dried roots of Scutellaria baicalensis Georgi., based on traditional Chinese medicine is bitter in taste and cold in nature with the actions of eliminating heat and resolving dampness, purging fire and removing toxic materials, and arresting bleeding and calming fetus, and is major for discomfort in the chest, nausea and vomiting in eidemic febrile diseases caused by damp-heat or summer-heat; feeling of stuffiness in the abdomen, acute dysentery or jaundice caused by damp-heat; cough due to heat in the lung; high fever with dire thirst; spitting of blood and epistaxis due to heat in blood; carbuncles and sores; threatened abortion. The herb, one traditional exportation herbal medicine, is utilized not only in simple or complex prescription, but also as major ingredients in manyChinese patent medicines, such as SanhuangPian, Shuanghuanglian oral solution and so on. A lot of research has been done on Radix Scutellariae in a few decades, and over 10 flavonoids, proved to be active ingredients in the herb, have be identified, among which baicalin, baicalein, wogonoside and wogonin exist in higher quantity. It has been conformed by pharmacology that baicalin has bacteriiostatic, hypeotensive, diuretic, anti-inflammatory and anti-allergic effects as well as the actions of calmness and chologogue; baicalein has bacteriiostatic, diuretic, anti-inflammatory and Anti-allergic effects; and wogonin has bacteriiostatic and diuretic effects, and action of relaxing the spasms. Radix Scutellariae used in preparations is regarded as major medicine for treatment of respiratory tract infection, virus hepatitis, trauma, local infection, scald and so on, with no obvious side effects. The antioxidative action of Radix Scutellariae has been studied by pharmacology in recent a few years and it has been conformed that Baicalin and baicalein have stronger scavenging effects on hydroxyl radical and superoxygen radical. The herb can inhibit inflammatory reaction and has effects of the antibacterial and anti-virus, and anti-tumor and preventing cancer.Bulbus Fritillariae, one of traditional Chinese herbal medicines, is the dried bulb of several species of genus Fritillaria, family Liliaceae. It is bitter in taste and cold in nature with the effects of clearing away heat and nourishing the lung, eliminating phlegm and relieving cough, dispersing stagnation and relieving carbuncles and so on, for treatment of cough due to phlegm and heat,scrofula and goiter, sore and ulcer, etc. Bulbus Fritillariae Hupehensis, embodied in Part one in Chinese Pharmacopia and also called as Ebei, Yaobei, Fongbei, has been used for a long time in Hubei and has became the second major used Bulbus Fritillariae goods only inferior to Bulbus Fritillariae Thunbergii. The active components in the herb are mainly alkaloids. Additionally, P-sitosterol and adenosine exist in higher content. It has been reported that P-sitosterol has the effects of relieving cough, and that adenosine has the actions of relaxing bronchial tube smooth muscle and anti-inflammatory, which may play certain action on eliminating phlegm and relieving cough in Bulbus Fritillariae Hupehensis. Bulbus Fritillariae has the effects of stopping cough, eliminating phlegm, relieving asthma and antitumor.Radix Scutellariae and Bulbus Fritillariae, used as major medicine, are assisted by Semen Armeniacae Amarum, Cortex Mori Radicis, and aided by Radix Platycodi and Folium Peri...