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Type2Diabetes Associated With Nonalcoholic Fatty Liver Disease Related Factors And TCM Syndrome Analysis

Posted on:2013-02-24Degree:MasterType:Thesis
Country:ChinaCandidate:G WangFull Text:PDF
GTID:2234330374485148Subject:Traditional Chinese Medicine
Abstract/Summary:
Objective:This research through the analysis of type2diabetes mellitus (Type2Diabetes Mellitus, T2DM) complicated with non alcoholic fatty liver disease(nonal coholic fatty live disease, NAFLD) in patients with risk factors,as well as on TCM syndrome distribution, further elaborated NALFD possiblepathogenesis, combine traditional Chinese and Western medicine and to providethe theoretical and clinical basis.Method:2010May to2011October selection in Zaozhuang city hospital in168T2DMpatients, according to a NAFLD divided into NAFLD group (group NAFLD) in95cases and the control group (group NO-NAFLD) in73patients in two groups.Observation of two groups of patients with age, height, weight, body mass index(BMI), fasting plasma glucose (FPG), C peptide,2hC postprandial peptide,alanine transaminase (ALT), aspartate aminotransferase (AST),gamma-glutamyl transferase (GGT), total cholesterol (TC), triglyceride(TG), high density lipoprotein cholesterol (HDL-C), low density lipoproteincholesterol (LDL-C), glycosylated hemoglobin (HbA1c), uric acid (UA)and other indicators. According to the standard of syndrome differentiation,and statistics associated with fatty liver in patients with type proportion.Result:In1T2DM patients with NAFLD group and NO-NAFLD group compare, weight,BMI, fasting C peptide,2hC postprandial peptide, TG, HDL-C, ALT, AST, GGT andUA had a significant difference (P <0.01, P <0.05); age, height, TC, FBG,HbA1c and LDL-C comparison, difference no statistical significance (P>0.05). Multiple regression revealed: BMI, triglycerides are the influencing factorsof NAFLD.In2T2DM patients with NAFLD group and NO-NAFLD group compare, yindeficiency, blood stasis, deficiency of Qi, qi stagnation syndrome ofdamp-heat, no significant difference (P>0.05), but the two groups ofpatients with Qi deficiency and permit a proportion are higher, more than60%.Group NAFLD phlegm dampness syndrome than those in group NO-NAFLD (P <0.05).Conclusion:Type2diabetes associated with nonalcoholic liver patients with obesity,abnormal lipid metabolism, insulin resistance (IR). BMI, triglycerides areimportant risk factors.Type2diabetes associated with nonalcoholic fatty liver disease inpatients with phlegm dampness syndrome as its main pathogenesis of syndrome.
Keywords/Search Tags:Type2diabetes, nonalcoholic fatty liver, syndrome of traditionalChinese Medicine
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