Objective: To observe the Yishenhuoxue Fang treatment of kidney deficiency andblood ovarian reserve decline in the late menstruation, and too little effect and explore itsmechanism.Methods: select61cases of kidney deficiency and blood stasis ovarian reservedecline in the late menstruation, fewer patients, take random number table,.the treatmentgroup,31cases (taking Yishenhuoxue Fang),30patients (taking Kun Ling Wan), observecurative effects of the two groups before and after the treatment.The menstrual cycle,amount, by the improvement of the quality of the three main symptoms and systemicsymptoms,blood basis of FSH, LH, FSH/LH and E2level changes after treatment.Results: After treatment, TCM symptoms score between groups of very significantdifference (P <0.01); the levels of FSH, LH, FSH/LH in two groups decreased and E2levels rise than before treatment,there are very significant difference (P <0.01) within thegroup, a significant difference (P <0.05or P <0.01) between the two groups.Conclusion: The Yishenhuoxue Fang treatment of kidney deficiency and bloodovarian reserve decline in the late menstruation, too little is effect.The mechanism may beYishenhuoxue Fang improve blood circulation, improve the ovarian follicle number andfollicle quality, prompting the granulosa cells to produce more inhibin, thereby reducingthe FSH, LH, FSH/LH and increased the E2level, also it can promote ovarian growth,increase the number of follicles, thereby improving ovarian function to achievemenstruation and to improve the efficacy of clinical. |