The Clinical Study Of Body Acupuncture And Auricular Acupressure Treatment On Menstrual Headache Of Hyperactivity Of Liver Fire

Objective: Menstrual headache is a disease and syndrome refers to eachmenstrual period or before and after occurs with headache as the mainmanifestation. This disease is equivalent to modern medicine "menstrualmigraine", accounted for65%of women migraines, which is a commondisease gynecological. With the pace of modern life accelerates, the workingpressure increases and mental stress, its incidence is increasing year by year,which serious impact on women’ normal work and quality of life.At present, there are much modern medicine treatment on Menstrualheadache (such as sex hormones drugs, calcium channel blockers, sedativeanalgesic agents), although efficacy, but more adverse reactions, high recur-ence rate and poor long-term efficacy and certain side effects, so it still lack ofsatisfactory therapy currently. Traditional Chinese Medicine of acupuncture inthe treatment of this disease showed a clear advantage. Tutor found bodyacupuncture and auricular acupressure treatment on Menstrual headache onthe basis of TCM theories and clinical practice in the long-term exploration,based on the prevalence of the disease, she considered women due to theaccelerated pace of modern life, work pressure, mental stress, emotional notsmooth, easily lead to disharmony of thoroughfare and conception vessels andhyperactivity of liver fire, disturbing orifices, caused menstrual headache.According to its pathogenesis characteristics, formulates "conditioningthoroughfare and conception vessels, clearing and reducing liver fire, promot-ing meridian and relieving pain", selects Baihui, Fengchi, Sanyinjiao, Tai-chong, Xiaxi, Taiyang through to Hanyan, Hanyan through to Xuanlu, Xuanluthrough to Shuaigu, this disease and achieved good clinical efficacy.This study was designed to observe the patients of Menstrual headache ofhyperactivity of liver fire before and after treatment of headache symptom scores, VAS scores, pain starting the onset time and observe the changes in therelevant indicators, evaluates the clinical efficacy of Menstrual headache withbody acupuncture and auricular acupressure, explore its mechanism of action.To provide a safe and effective, simple, practical, non-toxic side effects ofnon-drug therapy for clinical treatment of this disease.Methods:95patients (from the Hebei Normal hospital during Mar.2010to Dec.2011) with Menstrual headache of hyperactivity of liver fire werechosen. They were randomly divided into treatment group (n=43) and controlgroup (n=42). All patients were to be selected in accordance with thediagnostic criteria and inclusion criteria. Treatment group: Treatments arebody acupuncture and auricular acupressure treatment.①Headache treatmentis body acupuncture and auricular acupressure. First, selected on the30th1.5to2inch needle needling Baihui, Fengchi, Sanyinjiao, Taichong, Xiaxi,Taiyang through to the Han yan, Hanyan through to the Xuanlu, Xuanluthrough to the Shuaigu, once a day, continuous treatment3d; then, auricularacupressure bilateral Shenmen, temporal, liver, gallbladder, cortex, sympa-thetic, patients to press3times a day after stickers pressure, continuoustreatment3d.②Conditioning treatment of premenstrual is auricularacupressure unilateral endocrine, ovarian, Shenmen, cortex, liver, spleen,kidney before3d of menstrual period, left and right ear use alternating,operating with the above instructions, treatment to menstrual cramps.Controlgroup: oral medicine Flunarizine Hydrochloride Capsules (Sibelium),5mgeach time, two times a day. Taking from before1week of menstrual period,continuous treatment2weeks. The two groups were treated with three courses(menstrual cycle). Follow-up three months, observe the two groups clinicalheadache symptom score and, VAS scores the course of Pain onset timebefore and after treatment. Treatment group and control group randomlyselected30patients were taken before treatment and follow-up the first month(after treatment) menstrual cramps within48h blood test serocym β-EP, ET-1,AVP content, blood serum PGF2α, PGE2. And set20cases for normal group(the female whose age between18to40years without menstrual headache, and normal and healthy), any time of menstrual cramps within24h, takesvenous blood to detect the corresponding biochemical indices and comparedwith other two groups. Record the observed indicators data before and aftertreatment. Data was analyzed by soft ware SPSS13.0.Results:1Comparison of curative effect of treatment and control groups: Thetotal effective rate of treatment group was95.35%, otherwise,80.95%ofcontrol group. The curative effect of treatment group was significantly betterthan the control group (P＜0.05). The overall effect of the two groups, thedifference was significant (P＜0.01). The treatment group and the controlgroup, the overall efficacy of different degree (mild, moderate, severe) byWilcoxon rank test, the total curative effect of treatment group obviouslysurpasses the comparison group (P＜0.01); mode-rate, severe treatment groupwas significantly better than the control group (P＜0.05), both the mild groupof treatment group and contronl group are effective (P＞0.05).2Comparison of headache symptom scores prior and post treatment:before treatment, the symptom score of two groups balanced, the differencewas not significant (P＞0.05).①Treatment group: patients with1st course oftreatment compared with2nd,3rd treatment and follow-up3months headachesymptom scores, the differences were very significant (P＜0.01). Comparisonof2nd,3rd treatment, the difference was significant (P＜0.01).②Controlgroup: patients with1st course of treatment compared with2nd,3rd treatmentand follow-up3months headache symptom scores, the differences weresignificant (P＜0.01or P＜0.05). Comparison of2nd,3rd treatment, thedifference was significant (P＜0.01).③Comparison of two groups: The twogroups before treatment and course of2nd,3rd and follow-up3months, thedifferences were very significant (P＜0.01). Indicates that two groups of eachcourse of treatment and follow-up after three months of symptom scores weresignificantly lower, and the treatment group decreased more significantly, thetreatment group better than the control group. 3Comparison of VAS scores prior and post treatment: before treatment,the VAS scores of two groups balanced, the difference was not significant (P＞0.05).①Treatment group: Comparison of the1st course prior and posttreatment, the differences were very significant (P＜0.01); patients with1stcourse of treatment compared with2nd,3rd treatment and follow-up3monthsheadache VAS scores, the differences were very significant (P＜0.01);Comparison of2nd,3rd treatment, the difference was significant (P＜0.01).②Control group: Comparison of the1st course prior and post treatment, thedifferences was very significant (P＜0.01); patients with1st course of treat-ment compared with2nd,3rd treatment and follow-up3months headacheVAS scores, the differences were significant (P＜0.01or P＜0.05); Compar-ison of2nd,3rd treatment, the difference was no significant (P＞0.05).③Comparison of two groups: Two groups after the end of the first course oftreatment, the difference was significant (P＜0.01)；comparison of the twogroups course of2nd, the difference was not significant(P＞0.05); comparisonof the two groups course of3rd and follow-up3months, there differencewere very significant (P＜0.01). Indicates that two groups of each course oftreatment and follow-up after three months of VAS scores were significantlylower, and the treatment group decreased more significantly, the treatmentgroup better than the control group.4Comparison of the course of two groups after the pain onset time: Afterthe end of the two groups of1st course after pain onset and end of the2ndcourse, the differences were no significant (P＞0.05); after the end of the twogroups of3rd course and after pain onset and end of the1st course, thedifferences were very significant(P＜0.01); after the end of the treatmentgroup of3rd course and after pain onset and end of the2nd course, thedifferences was significant(P＜0.05), after the end of the control group of3rdcourse and after pain onset and end of the2nd course, the differences was nosignificant(P＞0.05); after the end of the treatment group of1st,2nd,3rdcourse pain onset compared with control groups the corresponding course, thedifferences were very significant (P＜0.01). Indicates that the course of the two groups after the end of the treatment of pain onset time both has shortened,particularly in the3rd course pain onset time shortened significantly after theend of treatment, and treatment group significantly better than control group.5Comparison of related Biochemical indices before and after treatmentof two groups: Treatment group and control group pre-treatment of plasmaAVP, ET-1and serum PGF2αcontent and PGF2α/PGE2ratio than the normalgroup were significantly increased (P＜0.01); plasma β-ΕΡ and serum PGE2,NO content has significantly lower than normal group, the differences werestatistically significant (P＜0.01). After treatment, the plasma AVP, ET-1andserum PGF2αcontent and PGF2α/PGE2ratio of treatment group and controlgroup were significantly lower than pre-treatment, the differences werestatistically significant (P＜0.01); plasma β-ΕΡ and serum PGE2, NO contentwere significantly increased than pre-treatment, the differences were statistic-cally significant(P＜0.01). After treatment, plasma ET-1and serum PGF2αandPGE2content and PGF2α/PGE2ratio of treatment group change more signifi-cant than control group, the differences were statistically significant (P＜0.01or P＜0.05), plasma β-ΕΡ, AVP and serum NO content were no statisticallydifferences than control group (P＞0.05).After treatment, the plasma ET-1and serum PGF2αand PGE2content andPGF2α/PGE2ratio of treatment group without significant difference thannormal group (P＞0.05); the plasma AVP, ET-1and serum PGF2α, NO contentof control group were no statistically differences than normal group (P＞0.05);but plasma ET-1and serum PGE2content and PGF2α/PGE2ratio of controlgroup has statistically differences than normal group (P＜0.01or P＜0.05).Conclusion:1Both body acupuncture and auricular acupressure and oral Sibelium canbe lower in patients with headache symptom score and VAS scores, shortenpain onset time, but before therapeutic treatment are superior to the latter.Explained that both two treatment methods have better analgesic effect, whichcan effectively improve headache symptoms, reduce the degree of pain,shorten the duration of pain, and body acupuncture and auricular acupressure and stronger analgesic effect, not only the instant analgesic effect, but thelong-term effects, exact clinical efficacy.2Both body acupuncture and auricular acupressure and oral Sibelium canreduce patients of Menstrual headache of hyperactivity of liver fire plasmaAVP, ET-1and serum PGF2αcontent and PGF2α/PGE2ratio; improve plasmaβ-ΕΡ and serum PGE2, NO content, and body acupuncture and auricularacupressure therapy makes the index restored to the normal level. Twotreatment methods have good regulation on plasma β-ΕΡ、AVP、ET-1andserum PGF2α, PGE2, NO content, but the former regulation is more obvious,which can be adjusted further neurohormone and abnormal levels of vocativesubstances, improving systolic and diastolic function of the head vascularsmooth muscle to play the analgesic effect.3Body acupuncture and auricular acupressure therapy, with no adversereactions in clinical application, which can avoid side effects such asdrowsiness, fatigue, depression, gastrointestinal symptoms caused by Sibelium,is a safe and reliable therapy.4Body acupuncture and auricular acupressure is a treatment method withsafe and effective, simple, non-toxic side effects treatment on Menstrualheadache of hyperactivity of liver fire.