Research On The Applications Of Cardiovascular Function Evaluation For Patients With Hypertensive Disorder Complicating Pregnancy By The Instantaneous Wave Intensity

Objectives：Research on the clinical value of wave intensity in evaluation of cardiovascularfunction for the patients with hypertensive disorder complicating pregnancy.Methods：This paper selected28pregnancy women with hypertensive disorder including15cases with gestational hypertension and13cases with pre-eclampsia, and31normal pregnant women as the control. Aloka Prosound a10color dopplerimaging was used to measure parameters. Firstly, selected Adult Heart Processand sweeped heart, then, received left ventricular function parameters: cardiacoutput（CO for short）, cardiac index（CI for short）, stroke volume（SV forshort）, left ventricular ejection fraction（LVEF for short）, left ventricularfractional shortening（LVFS for short）, peak early diastolic velocity of mitralflow （E peak for short）, peak late diastolic velocity of mitral flow（A peak forshort） and ratio of late tow（E/A for short）. Selected the WI process andsweeped common carotid artery, the WI Parameters were received as follow:transient acceleration wave intensity （W1for short） and transient decelerationwave intensity （W2for short） and arterial elastic parameters: carotid arterialstiffness index （β for short）, contingency coefficient of pressure （Eρ for short）and compliance （AC for short）. Lately, the correlation among some parameterswas analyzed.Results:Contractive pressure, diastolic blood pressure and mean blood pressureincreased Significantly throughout pregnancy, peaked in pre-eclampsia（P<0.01）. The CO increased predominantly in pre-eclampsia （P <0.05）. TheHeight, body surface area （BSA for short）, heart rate （HR for short） were nostatistical significance （P>0.05）. The LVEF was statistical significance betweengestational hypertension, pre-eclampsia and normal Pregnancy women （P<0.05）. The parameters of left ventricular structure such as left ventricularend-systole dimension （LVEDS for short）, left ventricular end-diastolicdiameter （LVEDd for short）, Inter-ventricular septal thickness （IVST for short）,post wall thickness （PWT for short） of patients with preeclampsia weresignificantly higher than those of normal pregnant women,（P<0.05）. Thecardiac index（CI for short）, stroke volume（SV for short） were no statisticalsignificance between gestational hypertension, pre-eclampsia and normalpregnancy women （P>0.05）. The CO of patients with pre-eclampsia weresignificantly higher than those of normal pregnant women,（P<0.05） while theejection fraction EF were significantly lower than that of normal pregnantwomen,（P<0.05）. Common carotid artery: transient acceleration were lower inpre-eclampsia than that in gestational hypertension group（P<0.05）. The β wassignificantly higher in pre-eclampsia than that in control group （P<0.01）. The βwas higher in pre-eclampsia than that in gestational hypertensiongroup（P<0.05）. The Eρ and PWVβ was significantly higher in pre-eclampsiathan that in control group （P<0.01）. The NA of patients with pre-eclampsiawere significantly higher than those of normal pregnant women,（P<0.05）. TheW₂, AC, AI, R-W₁, W₁-W₂, was no statistical significance between gestationalhypertension, pre-eclampsia and normal pregnancy women （P>0.05）.Conclusions：The value of WI for preeclampsia in this study group is higher than thegestational hypertension group （P <0.05）, and differences of the EF valuebetween the two groups is statistically significant. Therefore, the WI is betterthan the EF and FS in the evaluation of systolic function for patients withpregnancy-induced hypertension （PIH）. The Ep, β, PWVβ, AC of preeclampsiagroup is higher than the control group with normal pregnancy significantly. Theresults showed that pregnancy-induced hypertension in patients with carotidartery compliance decreased, increased arterial stiffness and decreased arterial elasticity. As a reflection of the new indicators of cardiac and vascular function,WI could be used for function evaluation of left ventricular systolic anddiastolic, as so as early evaluation of endothelial function in patients with PIHbefore the morphological changes of peripheral vascular. The paper provides anew, rapid, noninvasive and reliable method for the clinical prediction of PIHdisease progression and outcome.